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Young adult psychological outcome after puberty suppression and gender reassignment.

de Vries AL, McGuire JK, Steensma TD, Wagenaar EC, Doreleijers TA, Cohen-Kettenis PT. de Vries AL, et al. Among authors: wagenaar ec. Pediatrics. 2014 Oct;134(4):696-704. doi: 10.1542/peds.2013-2958. Epub 2014 Sep 8. Pediatrics. 2014. PMID: 25201798

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[Acute kidney injury, an avoidable problem].

van Vugt LK, Wagenaar E, van Etten RW. van Vugt LK, et al. Among authors: wagenaar e. Ned Tijdschr Geneeskd. 2021 Apr 8;165:D5528. Ned Tijdschr Geneeskd. 2021. PMID: 33914430 Dutch.

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Multidrug resistance and the role of P-glycoprotein knockout mice.

Schinkel AH, Mol CA, Wagenaar E, van Deemter L, Smit JJ, Borst P. Schinkel AH, et al. Among authors: wagenaar e. Eur J Cancer. 1995 Jul-Aug;31A(7-8):1295-8. doi: 10.1016/0959-8049(95)00130-b. Eur J Cancer. 1995. PMID: 7577039 Review.

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Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals.

Borst P, Schinkel AH, Smit JJ, Wagenaar E, Van Deemter L, Smith AJ, Eijdems EW, Baas F, Zaman GJ. Borst P, et al. Among authors: wagenaar e. Pharmacol Ther. 1993 Nov;60(2):289-99. doi: 10.1016/0163-7258(93)90011-2. Pharmacol Ther. 1993. PMID: 7912835 Review.

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ABC transporters Mdr1a/1b, Bcrp1, Mrp2 and Mrp3 determine the sensitivity to PhIP/DSS-induced colon carcinogenesis and inflammation.

Durmus S, van der Valk M, Teunissen SF, Song JY, Wagenaar E, Beijnen JH, Schinkel AH. Durmus S, et al. Among authors: wagenaar e. Arch Toxicol. 2019 Mar;93(3):775-790. doi: 10.1007/s00204-019-02394-w. Epub 2019 Jan 30. Arch Toxicol. 2019. PMID: 30701287

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Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.

Vasilyeva A, Durmus S, Li L, Wagenaar E, Hu S, Gibson AA, Panetta JC, Mani S, Sparreboom A, Baker SD, Schinkel AH. Vasilyeva A, et al. Among authors: wagenaar e. Cancer Res. 2015 Jul 1;75(13):2729-36. doi: 10.1158/0008-5472.CAN-15-0280. Epub 2015 May 7. Cancer Res. 2015. PMID: 25952649 Free PMC article.

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Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

van Hoppe S, Jamalpoor A, Rood JJM, Wagenaar E, Sparidans RW, Beijnen JH, Schinkel AH. van Hoppe S, et al. Among authors: wagenaar e. Pharmacol Res. 2019 Aug;146:104297. doi: 10.1016/j.phrs.2019.104297. Epub 2019 Jun 5. Pharmacol Res. 2019. PMID: 31175939

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P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.

Wang J, Gan C, Sparidans RW, Wagenaar E, van Hoppe S, Beijnen JH, Schinkel AH. Wang J, et al. Among authors: wagenaar e. Pharmacol Res. 2018 Mar;129:414-423. doi: 10.1016/j.phrs.2017.11.006. Epub 2017 Nov 14. Pharmacol Res. 2018. PMID: 29155017

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P-glycoprotein (MDR1/ABCB1) restricts brain accumulation and cytochrome P450-3A (CYP3A) limits oral availability of the novel ALK/ROS1 inhibitor lorlatinib.

Li W, Sparidans RW, Wang Y, Lebre MC, Wagenaar E, Beijnen JH, Schinkel AH. Li W, et al. Among authors: wagenaar e. Int J Cancer. 2018 Oct 15;143(8):2029-2038. doi: 10.1002/ijc.31582. Epub 2018 Jul 10. Int J Cancer. 2018. PMID: 29744867 Free article.

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WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.

Bailey JK, Fields AT, Cheng K, Lee A, Wagenaar E, Lagrois R, Schmidt B, Xia B, Ma D. Bailey JK, et al. Among authors: wagenaar e. J Biol Chem. 2015 Apr 3;290(14):8987-9001. doi: 10.1074/jbc.M114.623611. Epub 2015 Feb 9. J Biol Chem. 2015. PMID: 25666610 Free PMC article.

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