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Deepen into sleep and wake patterns across Alzheimer's disease phenotypes.
Falgàs N, Walsh CM, Neylan TC, Grinberg LT. Falgàs N, et al. Among authors: walsh cm. Alzheimers Dement. 2021 Aug;17(8):1403-1406. doi: 10.1002/alz.12304. Epub 2021 Mar 12. Alzheimers Dement. 2021. PMID: 33710762 Free PMC article.
Although, the clinical variants of Alzheimer's disease (AD) show distinct patterns of cognitive and behavioral decline, disease progression, and neuropathological features, it is unclear if this clinical heterogeneity extends to sleep-wake patterns. ...Still, sle
Although, the clinical variants of Alzheimer's disease (AD) show distinct patterns of cognitive and behavioral decline, disease progr …
The role of co-neurotransmitters in sleep and wake regulation.
Oh J, Petersen C, Walsh CM, Bittencourt JC, Neylan TC, Grinberg LT. Oh J, et al. Among authors: walsh cm. Mol Psychiatry. 2019 Sep;24(9):1284-1295. doi: 10.1038/s41380-018-0291-2. Epub 2018 Oct 30. Mol Psychiatry. 2019. PMID: 30377299 Free PMC article. Review.
Sleep and wakefulness control in the mammalian brain requires the coordination of various discrete interconnected neurons. According to the most conventional sleep model, wake-promoting neurons (WPNs) and sleep-promoting neurons (SPNs) compete for network dom
Sleep and wakefulness control in the mammalian brain requires the coordination of various discrete interconnected neurons. According
Cognitive neuroscience of sleep.
Poe GR, Walsh CM, Bjorness TE. Poe GR, et al. Among authors: walsh cm. Prog Brain Res. 2010;185:1-19. doi: 10.1016/B978-0-444-53702-7.00001-4. Prog Brain Res. 2010. PMID: 21075230 Free PMC article. Review.
The extensive overlap between sleep mechanisms and the neurophysiology of learning and memory processes provide a foundation for theories of a functional link between the sleep and learning systems. ...The chapter reviews the results of manipulation studies, typical …
The extensive overlap between sleep mechanisms and the neurophysiology of learning and memory processes provide a foundation for theo …
Specific cortical and subcortical grey matter regions are associated with insomnia severity.
Falgàs N, Illán-Gala I, Allen IE, Mumford P, Essanaa YM, Le MM, You M, Grinberg LT, Rosen HJ, Neylan TC, Kramer JH, Walsh CM. Falgàs N, et al. Among authors: walsh cm. PLoS One. 2021 May 26;16(5):e0252076. doi: 10.1371/journal.pone.0252076. eCollection 2021. PLoS One. 2021. PMID: 34038462 Free PMC article.
Therefore, our goal was to investigate GM changes associated with insomnia severity in a cohort of healthy older adults, taking into account the potential effect of depression and sleep apnea as well. We hypothesized that insomnia severity is correlated with 1) cortical re …
Therefore, our goal was to investigate GM changes associated with insomnia severity in a cohort of healthy older adults, taking into account …
The relationship between child and caregiver sleep in acute lymphoblastic leukemia maintenance.
Daniel LC, Walsh CM, Meltzer LJ, Barakat LP, Kloss JD. Daniel LC, et al. Among authors: walsh cm. Support Care Cancer. 2018 Apr;26(4):1123-1132. doi: 10.1007/s00520-017-3933-z. Epub 2017 Oct 18. Support Care Cancer. 2018. PMID: 29046955 Free PMC article.
METHODS: Caregivers of 68 children with ALL, ages 3 to 12 years old, completed measures of caregiver guilt and worry, caregiver sleep quality, and child's developmental history and sleep habits. ...Further research on the timing of sleep interventions …
METHODS: Caregivers of 68 children with ALL, ages 3 to 12 years old, completed measures of caregiver guilt and worry, caregiver sleep
REM sleep is associated with white matter integrity in cognitively healthy, older adults.
Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM. Altendahl M, et al. Among authors: walsh cm. PLoS One. 2020 Jul 9;15(7):e0235395. doi: 10.1371/journal.pone.0235395. eCollection 2020. PLoS One. 2020. PMID: 32645032 Free PMC article.
Less is known, however, about how objectively measured sleep associates with brain structure. We objectively measured at-home sleep to investigate how sleep architecture and sleep quality related to white matter microstructure in older adults. 43 cogni …
Less is known, however, about how objectively measured sleep associates with brain structure. We objectively measured at-home slee
Sleepless Night and Day, the Plight of Progressive Supranuclear Palsy.
Walsh CM, Ruoff L, Walker K, Emery A, Varbel J, Karageorgiou E, Luong PN, Mance I, Heuer HW, Boxer AL, Grinberg LT, Kramer JH, Miller BL, Neylan TC. Walsh CM, et al. Sleep. 2017 Nov 1;40(11):zsx154. doi: 10.1093/sleep/zsx154. Sleep. 2017. PMID: 29029214 Free PMC article.

Data were assessed for measures of latency to sleep onset, sleep duration, waking, and sleep staging during the night. ...RESULTS: PSP took significantly longer time to fall asleep (p < .001), slept less during the night (p .001), and had more wake after

Data were assessed for measures of latency to sleep onset, sleep duration, waking, and sleep staging during the night. …
Rest-activity rhythm disruption in progressive supranuclear palsy.
Walsh CM, Ruoff L, Varbel J, Walker K, Grinberg LT, Boxer AL, Kramer JH, Miller BL, Neylan TC. Walsh CM, et al. Sleep Med. 2016 Jun;22:50-56. doi: 10.1016/j.sleep.2016.05.002. Epub 2016 Jun 21. Sleep Med. 2016. PMID: 27544836 Free PMC article.
OBJECTIVE/BACKGROUND: The brainstem is among the first regions affected in progressive supranuclear palsy (PSP) and is part of the sleep/circadian regulation network. In two small studies, blood pressure and core body temperature circadian patterns were disrupted in PSP; h …
OBJECTIVE/BACKGROUND: The brainstem is among the first regions affected in progressive supranuclear palsy (PSP) and is part of the sleep
Profound degeneration of wake-promoting neurons in Alzheimer's disease.
Oh J, Eser RA, Ehrenberg AJ, Morales D, Petersen C, Kudlacek J, Dunlop SR, Theofilas P, Resende EDPF, Cosme C, Alho EJL, Spina S, Walsh CM, Miller BL, Seeley WW, Bittencourt JC, Neylan TC, Heinsen H, Grinberg LT. Oh J, et al. Among authors: walsh cm. Alzheimers Dement. 2019 Oct;15(10):1253-1263. doi: 10.1016/j.jalz.2019.06.3916. Epub 2019 Aug 12. Alzheimers Dement. 2019. PMID: 31416793 Free PMC article.
INTRODUCTION: Sleep-wake disturbances are a common and early feature in Alzheimer's disease (AD). ...Considering that WPNs are involved early in AD, such degeneration should be included in the models explaining sleep-wake disturbances in AD and considered whe …
INTRODUCTION: Sleep-wake disturbances are a common and early feature in Alzheimer's disease (AD). ...Considering that WPNs are …
A "Sleep 101" Program for College Students Improves Sleep Hygiene Knowledge and Reduces Maladaptive Beliefs about Sleep.
Kloss JD, Nash CO, Walsh CM, Culnan E, Horsey S, Sexton-Radek K. Kloss JD, et al. Among authors: walsh cm. Behav Med. 2016;42(1):48-56. doi: 10.1080/08964289.2014.969186. Epub 2015 Jan 29. Behav Med. 2016. PMID: 25268924 Clinical Trial.
The sleep monitoring group received a sleep hygiene handout and completed sleep logs for the study duration. Sleep 101 participants endorsed fewer maladaptive beliefs and attitudes about sleep, increased sleep hygiene knowledge, and reduc …
The sleep monitoring group received a sleep hygiene handout and completed sleep logs for the study duration. Sleep
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