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Chemical Modifications of mRNA Ends for Therapeutic Applications.
Warminski M, Mamot A, Depaix A, Kowalska J, Jemielity J. Warminski M, et al. Acc Chem Res. 2023 Oct 17;56(20):2814-2826. doi: 10.1021/acs.accounts.3c00442. Epub 2023 Oct 2. Acc Chem Res. 2023. PMID: 37782471 Free PMC article.
2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion.
Drazkowska K, Tomecki R, Warminski M, Baran N, Cysewski D, Depaix A, Kasprzyk R, Kowalska J, Jemielity J, Sikorski PJ. Drazkowska K, et al. Among authors: warminski m. Nucleic Acids Res. 2022 Sep 9;50(16):9051-9071. doi: 10.1093/nar/gkac722. Nucleic Acids Res. 2022. PMID: 36018811 Free PMC article.
Trinucleotide mRNA Cap Analogue N6-Benzylated at the Site of Posttranscriptional m6Am Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo.
Warminski M, Trepkowska E, Smietanski M, Sikorski PJ, Baranowski MR, Bednarczyk M, Kedzierska H, Majewski B, Mamot A, Papiernik D, Popielec A, Serwa RA, Shimanski BA, Sklepkiewicz P, Sklucka M, Sokolowska O, Spiewla T, Toczydlowska-Socha D, Warminska Z, Wolosewicz K, Zuberek J, Mugridge JS, Nowis D, Golab J, Jemielity J, Kowalska J. Warminski M, et al. J Am Chem Soc. 2024 Mar 27;146(12):8149-8163. doi: 10.1021/jacs.3c12629. Epub 2024 Mar 5. J Am Chem Soc. 2024. PMID: 38442005 Free PMC article.
RNA Ligation for Mono and Dually Labeled RNAs.
Depaix A, Mlynarska-Cieslak A, Warminski M, Sikorski PJ, Jemielity J, Kowalska J. Depaix A, et al. Among authors: warminski m. Chemistry. 2021 Aug 19;27(47):12190-12197. doi: 10.1002/chem.202101909. Epub 2021 Jul 5. Chemistry. 2021. PMID: 34114681
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