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CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability.
Nozaki Y, Honda Y, Watanabe H, Saiki S, Koyabu K, Itoh T, Nagasawa C, Nakamori C, Nakayama C, Iwasaki H, Suzuki S, Washio I, Takahashi E, Miyamoto K, Yamanishi A, Endo H, Shinozaki J, Nogawa H, Kunimatsu T. Nozaki Y, et al. Among authors: washio i. Regul Toxicol Pharmacol. 2016 Jun;77:75-86. doi: 10.1016/j.yrtph.2016.02.007. Epub 2016 Feb 13. Regul Toxicol Pharmacol. 2016. PMID: 26884090
CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia--effects of 7 reference compounds at 10 facilities.
Kitaguchi T, Moriyama Y, Taniguchi T, Ojima A, Ando H, Uda T, Otabe K, Oguchi M, Shimizu S, Saito H, Morita M, Toratani A, Asayama M, Yamamoto W, Matsumoto E, Saji D, Ohnaka H, Tanaka K, Washio I, Miyamoto N. Kitaguchi T, et al. Among authors: washio i. J Pharmacol Toxicol Methods. 2016 Mar-Apr;78:93-102. doi: 10.1016/j.vascn.2015.12.002. Epub 2015 Dec 4. J Pharmacol Toxicol Methods. 2016. PMID: 26657830
14 results