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Page 1
Targeted nonviral delivery of genome editors in vivo.
Tsuchida CA, Wasko KM, Hamilton JR, Doudna JA. Tsuchida CA, et al. Among authors: wasko km. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307796121. doi: 10.1073/pnas.2307796121. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437567 Free PMC article. Review.
Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing.
Shi H, Al-Sayyad N, Wasko KM, Trinidad MI, Doherty EE, Vohra K, Boger RS, Colognori D, Cofsky JC, Skopintsev P, Bryant Z, Doudna JA. Shi H, et al. Among authors: wasko km. Mol Cell. 2025 May 1;85(9):1730-1742.e9. doi: 10.1016/j.molcel.2025.03.024. Epub 2025 Apr 23. Mol Cell. 2025. PMID: 40273916 Free article.
Directed evolution expands CRISPR-Cas12a genome editing capacity.
Ma E, Chen K, Shi H, Wasko KM, Esain-Garcia I, Trinidad MI, Zhou K, Ye J, Doudna JA. Ma E, et al. Among authors: wasko km. bioRxiv [Preprint]. 2025 Mar 26:2025.03.26.645588. doi: 10.1101/2025.03.26.645588. bioRxiv. 2025. PMID: 40196639 Free PMC article. Preprint.
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA. Adler BA, et al. Among authors: wasko km. Nucleic Acids Res. 2024 Jan 5;52(D1):D590-D596. doi: 10.1093/nar/gkad890. Nucleic Acids Res. 2024. PMID: 37889041 Free PMC article.
Choosing Wisely Canada recommendations.
Wasko K. Wasko K. Can Fam Physician. 2018 Jan;64(1):39. Can Fam Physician. 2018. PMID: 29358249 Free PMC article. No abstract available.
Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing.
Shi H, Al-Sayyad N, Wasko KM, Trinidad MI, Doherty EE, Vohra K, Boger RS, Colognori D, Cofsky JC, Skopintsev P, Bryant Z, Doudna JA. Shi H, et al. Among authors: wasko km. bioRxiv [Preprint]. 2024 Oct 2:2024.10.01.616117. doi: 10.1101/2024.10.01.616117. bioRxiv. 2024. Update in: Mol Cell. 2025 May 1;85(9):1730-1742.e9. doi: 10.1016/j.molcel.2025.03.024. PMID: 40376084 Free PMC article. Updated. Preprint.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines.
Zhang L, Zuris JA, Viswanathan R, Edelstein JN, Turk R, Thommandru B, Rube HT, Glenn SE, Collingwood MA, Bode NM, Beaudoin SF, Lele S, Scott SN, Wasko KM, Sexton S, Borges CM, Schubert MS, Kurgan GL, McNeill MS, Fernandez CA, Myer VE, Morgan RA, Behlke MA, Vakulskas CA. Zhang L, et al. Among authors: wasko km. Nat Commun. 2021 Jun 23;12(1):3908. doi: 10.1038/s41467-021-24017-8. Nat Commun. 2021. PMID: 34162850 Free PMC article.
A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand.
Mikhailova AG, Mikhailova AA, Ushakova K, Tretiakov EO, Iliushchenko D, Shamansky V, Lobanova V, Kozenkov I, Efimenko B, Yurchenko AA, Kozenkova E, Zdobnov EM, Makeev V, Yurov V, Tanaka M, Gostimskaya I, Fleischmann Z, Annis S, Franco M, Wasko K, Denisov S, Kunz WS, Knorre D, Mazunin I, Nikolaev S, Fellay J, Reymond A, Khrapko K, Gunbin K, Popadin K. Mikhailova AG, et al. Among authors: wasko k. Nucleic Acids Res. 2022 Oct 14;50(18):10264-10277. doi: 10.1093/nar/gkac779. Nucleic Acids Res. 2022. PMID: 36130228 Free PMC article.
20 results