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The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition.
Lee K, Vakili S, Burden HJ, Adams S, Smith GC, Kulatea B, Wright-McNaughton M, Sword D, Watene-O'Sullivan C, Atiola RD, Paul RG, Plank LD, Kallingappa P, King F, Wilcox P, Merriman TR, Krebs JD, Hall RM, Murphy R, Merry TL, Shepherd PR. Lee K, et al. Among authors: watene o sullivan c. Mol Metab. 2022 May;59:101464. doi: 10.1016/j.molmet.2022.101464. Epub 2022 Feb 24. Mol Metab. 2022. PMID: 35218947 Free PMC article.
The CREBRF diabetes-protective rs373863828-A allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry.
Burden HJ, Adams S, Kulatea B, Wright-McNaughton M, Sword D, Ormsbee JJ, Watene-O'Sullivan C, Merriman TR, Knopp JL, Chase JG, Krebs JD, Hall RM, Plank LD, Murphy R, Shepherd PR, Merry TL. Burden HJ, et al. Among authors: watene o sullivan c. Diabetologia. 2021 Dec;64(12):2779-2789. doi: 10.1007/s00125-021-05552-x. Epub 2021 Aug 21. Diabetologia. 2021. PMID: 34417843