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Page 1
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R. Leppek K, et al. Among authors: wayment steele hk. Nat Commun. 2022 Mar 22;13(1):1536. doi: 10.1038/s41467-022-28776-w. Nat Commun. 2022. PMID: 35318324 Free PMC article.
Variational encoding of complex dynamics.
Hernández CX, Wayment-Steele HK, Sultan MM, Husic BE, Pande VS. Hernández CX, et al. Among authors: wayment steele hk. Phys Rev E. 2018 Jun;97(6-1):062412. doi: 10.1103/PhysRevE.97.062412. Phys Rev E. 2018. PMID: 30011547 Free PMC article.
Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular switches.
Andreasson JOL, Gotrik MR, Wu MJ, Wayment-Steele HK, Kladwang W, Portela F, Wellington-Oguri R; Eterna Participants; Das R, Greenleaf WJ. Andreasson JOL, et al. Among authors: wayment steele hk. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2112979119. doi: 10.1073/pnas.2112979119. Epub 2022 Apr 26. Proc Natl Acad Sci U S A. 2022. PMID: 35471911 Free PMC article.
Deep learning models for predicting RNA degradation via dual crowdsourcing.
Wayment-Steele HK, Kladwang W, Watkins AM, Kim DS, Tunguz B, Reade W, Demkin M, Romano J, Wellington-Oguri R, Nicol JJ, Gao J, Onodera K, Fujikawa K, Mao H, Vandewiele G, Tinti M, Steenwinckel B, Ito T, Noumi T, He S, Ishi K, Lee Y, Öztürk F, Chiu KY, Öztürk E, Amer K, Fares M; Eterna Participants; Das R. Wayment-Steele HK, et al. Nat Mach Intell. 2022;4(12):1174-1184. doi: 10.1038/s42256-022-00571-8. Epub 2022 Dec 14. Nat Mach Intell. 2022. PMID: 36567960 Free PMC article.
19 results