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Page 1
A novel human gene (WDR25) encoding a 7-WD40-containing protein maps on 14q32.
Jin F, Dai J, Ji C, Gu S, Wu M, Qian J, Xie Y, Mao Y. Jin F, et al. Biochem Genet. 2004 Dec;42(11-12):419-27. doi: 10.1023/b:bigi.0000043954.64202.61. Biochem Genet. 2004. PMID: 15587985
We term it human WD40-repeat-containing gene 25 (WDR25) and this gene shows significant similarity with human pre-mRNA splicing factor 17. The WDR25 gene is mapped to chromosome 14q32 and contains seven exons. RT-PCR analysis shows that the WDR25 gene is wide …
We term it human WD40-repeat-containing gene 25 (WDR25) and this gene shows significant similarity with human pre-mRNA splicing facto …
Identification of novel gene fusions in high-grade serous ovarian carcinoma: implications for tumorigenesis and targeted therapy.
Masago K, Sasaki E, Fujita Y, Fujita S, Horio Y, Kuroda H, Ogasawara A, Tatsuno K, Aburatani H, Oda K, Hasegawa K, Matsushita H. Masago K, et al. Cancer Genet. 2025 Nov;298-299:159-168. doi: 10.1016/j.cancergen.2025.09.012. Epub 2025 Sep 29. Cancer Genet. 2025. PMID: 41072140
In addition, SLMAP::NTRK3 involves NTRK3, a known fusion partner. The remaining fusions, SWAP70::ZNF143, WDR25::YY1, and NR2F6::MYO9B, included partners with DNA-binding domains. CONCLUSIONS: This study identified candidate driver fusion genes and suggested new therapeutic …
In addition, SLMAP::NTRK3 involves NTRK3, a known fusion partner. The remaining fusions, SWAP70::ZNF143, WDR25::YY1, and NR2F6::MYO9B …
The Begain gene marks the centromeric boundary of the imprinted region on mouse chromosome 12.
Tierling S, Gasparoni G, Youngson N, Paulsen M. Tierling S, et al. Mamm Genome. 2009 Sep-Oct;20(9-10):699-710. doi: 10.1007/s00335-009-9205-6. Epub 2009 Jul 30. Mamm Genome. 2009. PMID: 19641963
Nevertheless, imprinting effects do not spread further centromeric to the Wdr25 gene, which is biallelically expressed as the previously studied neighbouring Wars and Yy1 genes....
Nevertheless, imprinting effects do not spread further centromeric to the Wdr25 gene, which is biallelically expressed as the previou …
New insights into genetic architecture of Guangxi indigenous chickens using whole-genome sequencing.
Yang Z, Xu W, Liu Y, Sun T, Xiao C, Zou L, Zeng L, Deng J, Yang X. Yang Z, et al. Poult Sci. 2025 Nov;104(11):105836. doi: 10.1016/j.psj.2025.105836. Epub 2025 Sep 11. Poult Sci. 2025. PMID: 40992329 Free PMC article.
Genome-wide selection scans identified strong signals between southern and northern populations, uncovering genes associated with pigmentation (BCO2, SOX10, GRM5, MC1R, MITF, EDN3), body size (IGF1, POU1F1, CDH12) and egg production (AKT3, WDR25). Additionally, comparative …
Genome-wide selection scans identified strong signals between southern and northern populations, uncovering genes associated with pigmentati …
Identification of candidate genomic regions for chicken egg number traits based on genome-wide association study.
Zhao X, Nie C, Zhang J, Li X, Zhu T, Guan Z, Chen Y, Wang L, Lv XZ, Yang W, Jia Y, Ning Z, Li H, Qu C, Wang H, Qu L. Zhao X, et al. BMC Genomics. 2021 Aug 10;22(1):610. doi: 10.1186/s12864-021-07755-3. BMC Genomics. 2021. PMID: 34376144 Free PMC article.
In this region, we have repeatedly identified four genes, in which YY1 (YY1 transcription factor) and WDR25 (WD repeat domain 25) have been shown to be related to oocytes and reproductive tissues, respectively, which implies that this region may be a candidate region under …
In this region, we have repeatedly identified four genes, in which YY1 (YY1 transcription factor) and WDR25 (WD repeat domain 25) hav …
Cloning of avian Delta-like 1 homolog gene: the biallelic expression of Delta-like 1 homolog in avian species.
Shin S, Han JY, Lee K. Shin S, et al. Poult Sci. 2010 May;89(5):948-55. doi: 10.3382/ps.2009-00572. Poult Sci. 2010. PMID: 20371847 Free article.
Comparative analysis of the gene clusters containing the Dlk1 gene revealed that Yy1, Wars, Wdr25, Begain, Dlk1, Dio3, and Ppp2r5c were found in the cluster of the chicken genome, but 3 genes (Meg3, Rtl1, and Meg8) between Dlk1 and deiodinase, iodothyronine, type III (Dio3 …
Comparative analysis of the gene clusters containing the Dlk1 gene revealed that Yy1, Wars, Wdr25, Begain, Dlk1, Dio3, and Ppp2r5c we …
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tšernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collée JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D'adamo AP, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, García-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guénel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, M… See abstract for full author list ➔ Perry JR, et al. Nature. 2014 Oct 2;514(7520):92-97. doi: 10.1038/nature13545. Epub 2014 Jul 23. Nature. 2014. PMID: 25231870 Free PMC article.
Menarche signals were enriched in imprinted regions, with three loci (DLK1-WDR25, MKRN3-MAGEL2 and KCNK9) demonstrating parent-of-origin-specific associations concordant with known parental expression patterns. ...
Menarche signals were enriched in imprinted regions, with three loci (DLK1-WDR25, MKRN3-MAGEL2 and KCNK9) demonstrating parent-of-ori …
Comparative Genomic Analysis Across Multiple Species to Identify Candidate Genes Associated with Important Traits in Chickens.
Zhang F, Chen H, Chang C, Zhou J, Zhang H. Zhang F, et al. Genes (Basel). 2025 May 24;16(6):627. doi: 10.3390/genes16060627. Genes (Basel). 2025. PMID: 40565519 Free PMC article.
Conclusions: Based on the annotation results from various databases, a functional search of the candidate genes and related literature reports, the following results were obtained: genes such as TBX22, LCORL, and GH were associated with chicken growth traits; genes such as A-FABP …
Conclusions: Based on the annotation results from various databases, a functional search of the candidate genes and related literature repor …