Wegerski CJ[au] - Search Results

Year	Number of Results
2004	1
2007	1
2010	1
2011	1
2017	1
2018	2
2019	2
2020	5
2021	2
2023	0

1

Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors.

Nilewski C, Michels TD, Xiang AX, Packard GK, Sprengeler PA, Eam B, Fish S, Thompson PA, Wegerski CJ, Ernst JT, Reich SH. Nilewski C, et al. Among authors: wegerski cj. Org Lett. 2020 Aug 21;22(16):6257-6261. doi: 10.1021/acs.orglett.0c01944. Epub 2020 Jul 30. Org Lett. 2020. PMID: 32806219

2

1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.

Nilewski C, Michels TD, Packard GK, Xiang AX, Sprengeler PA, Eam B, Fish S, Thompson PA, Wegerski CJ, Nevarez A, Clarine J, Sperry S, Ernst JT, Reich SH. Nilewski C, et al. Among authors: wegerski cj. Bioorg Med Chem Lett. 2021 Sep 1;47:128111. doi: 10.1016/j.bmcl.2021.128111. Epub 2021 Aug 2. Bioorg Med Chem Lett. 2021. PMID: 34353608

3

Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A.

Thompson PA, Eam B, Young NP, Fish S, Chen J, Barrera M, Howard H, Sung E, Parra A, Staunton J, Chiang GG, Gerson-Gurwitz A, Wegerski CJ, Nevarez A, Clarine J, Sperry S, Xiang A, Nilewski C, Packard GK, Michels T, Tran C, Sprengeler PA, Ernst JT, Reich SH, Webster KR. Thompson PA, et al. Among authors: wegerski cj. Mol Cancer Ther. 2021 Jan;20(1):26-36. doi: 10.1158/1535-7163.MCT-19-0973. Epub 2020 Oct 9. Mol Cancer Ther. 2021. PMID: 33037136

4

A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei.

Wegerski CJ, Hammond J, Tenney K, Matainaho T, Crews P. Wegerski CJ, et al. J Nat Prod. 2007 Jan;70(1):89-94. doi: 10.1021/np060464w. J Nat Prod. 2007. PMID: 17253855 Free PMC article.

5

Comparative disposition of dimethylaminoethanol and choline in rats and mice following oral or intravenous administration.

Shipkowski KA, Sanders JM, McDonald JD, Garner CE, Doyle-Eisele M, Wegerski CJ, Waidyanatha S. Shipkowski KA, et al. Among authors: wegerski cj. Toxicol Appl Pharmacol. 2019 Sep 1;378:114592. doi: 10.1016/j.taap.2019.05.011. Epub 2019 May 14. Toxicol Appl Pharmacol. 2019. PMID: 31100288 Free PMC article.

6

Disposition and metabolism of 2',2'"-Dithiobisbenzanilide in rodents following intravenous and oral administration and dermal application.

Garner CE, Wegerski CJ, Doyle-Eisele M, McDonald JD, Sanders JM, Moeller BC, Waidyanatha S. Garner CE, et al. Among authors: wegerski cj. Toxicol Rep. 2020 Jul 23;7:883-892. doi: 10.1016/j.toxrep.2020.07.006. eCollection 2020. Toxicol Rep. 2020. PMID: 32760656 Free PMC article.

7

Disposition of β-N-methylamino-l-alanine (L-BMAA), a neurotoxin, in rodents following a single or repeated oral exposure.

Waidyanatha S, Ryan K, Sanders JM, McDonald JD, Wegerski CJ, Doyle-Eisle M, Garner CE. Waidyanatha S, et al. Among authors: wegerski cj. Toxicol Appl Pharmacol. 2018 Jan 15;339:151-160. doi: 10.1016/j.taap.2017.12.008. Epub 2017 Dec 15. Toxicol Appl Pharmacol. 2018. PMID: 29248465

8

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.

Ernst JT, Thompson PA, Nilewski C, Sprengeler PA, Sperry S, Packard G, Michels T, Xiang A, Tran C, Wegerski CJ, Eam B, Young NP, Fish S, Chen J, Howard H, Staunton J, Molter J, Clarine J, Nevarez A, Chiang GG, Appleman JR, Webster KR, Reich SH. Ernst JT, et al. Among authors: wegerski cj. J Med Chem. 2020 Jun 11;63(11):5879-5955. doi: 10.1021/acs.jmedchem.0c00182. Epub 2020 May 29. J Med Chem. 2020. PMID: 32470302

9

Disposition and metabolism of cumene in F344 rats and B6C3F1 mice.

Chen LJ, Wegerski CJ, Kramer DJ, Thomas LA, McDonald JD, Dix KJ, Sanders JM. Chen LJ, et al. Among authors: wegerski cj. Drug Metab Dispos. 2011 Mar;39(3):498-509. doi: 10.1124/dmd.110.034769. Epub 2010 Nov 23. Drug Metab Dispos. 2011. PMID: 21098646 Free PMC article.

10

Metabolism and disposition of 2-hydroxy-4-methoxybenzophenone, a sunscreen ingredient, in Harlan Sprague Dawley rats and B6C3F1/N mice; a species and route comparison.

Mutlu E, Garner CE, Wegerski CJ, McDonald JD, McIntyre BS, Doyle-Eisele M, Waidyanatha S. Mutlu E, et al. Among authors: wegerski cj. Xenobiotica. 2020 Jun;50(6):689-704. doi: 10.1080/00498254.2019.1680906. Epub 2019 Oct 31. Xenobiotica. 2020. PMID: 31613170 Free PMC article.

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