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Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC.
Cho BC, Lu S, Felip E, Spira AI, Girard N, Lee JS, Lee SH, Ostapenko Y, Danchaivijitr P, Liu B, Alip A, Korbenfeld E, Mourão Dias J, Besse B, Lee KH, Xiong H, How SH, Cheng Y, Chang GC, Yoshioka H, Yang JC, Thomas M, Nguyen D, Ou SI, Mukhedkar S, Prabhash K, D'Arcangelo M, Alatorre-Alexander J, Vázquez Limón JC, Alves S, Stroyakovskiy D, Peregudova M, Şendur MAN, Yazici O, Califano R, Gutiérrez Calderón V, de Marinis F, Passaro A, Kim SW, Gadgeel SM, Xie J, Sun T, Martinez M, Ennis M, Fennema E, Daksh M, Millington D, Leconte I, Iwasawa R, Lorenzini P, Baig M, Shah S, Bauml JM, Shreeve SM, Sethi S, Knoblauch RE, Hayashi H; MARIPOSA Investigators. Cho BC, et al. N Engl J Med. 2024 Oct 24;391(16):1486-1498. doi: 10.1056/NEJMoa2403614. Epub 2024 Jun 26. N Engl J Med. 2024. PMID: 38924756 Clinical Trial.
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.
Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM; ODYSSEY OUTCOMES Committees and Investigators. Schwartz GG, et al. N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174. Epub 2018 Nov 7. N Engl J Med. 2018. PMID: 30403574 Free article. Clinical Trial.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.
Lawson KA, Sousa CM, Zhang X, Kim E, Akthar R, Caumanns JJ, Yao Y, Mikolajewicz N, Ross C, Brown KR, Zid AA, Fan ZP, Hui S, Krall JA, Simons DM, Slater CJ, De Jesus V, Tang L, Singh R, Goldford JE, Martin S, Huang Q, Francis EA, Habsid A, Climie R, Tieu D, Wei J, Li R, Tong AHY, Aregger M, Chan KS, Han H, Wang X, Mero P, Brumell JH, Finelli A, Ailles L, Bader G, Smolen GA, Kingsbury GA, Hart T, Kung C, Moffat J. Lawson KA, et al. Nature. 2020 Oct;586(7827):120-126. doi: 10.1038/s41586-020-2746-2. Epub 2020 Sep 23. Nature. 2020. PMID: 32968282 Free PMC article.
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Lee WJ, Hsiung CA, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Munz M, Zeng L, Huang J, Yang B, Poved… See abstract for full author list ➔ Ramdas S, et al. Am J Hum Genet. 2022 Aug 4;109(8):1366-1387. doi: 10.1016/j.ajhg.2022.06.012. Am J Hum Genet. 2022. PMID: 35931049 Free PMC article.
Cell damage evaluation by intelligent imaging flow cytometry.
Yao Y, He L, Mei L, Weng Y, Huang J, Wei S, Li R, Tian S, Liu P, Ruan X, Wang D, Zhou F, Lei C. Yao Y, et al. Cytometry A. 2023 Aug;103(8):646-654. doi: 10.1002/cyto.a.24731. Epub 2023 Mar 31. Cytometry A. 2023. PMID: 36966466 Free article.
Specifically, we first image the erythrocytes and leukocytes sorted by acoustofluidic sorting chip with different acoustic wave powers and flowing speed using OTS imaging flow cytometry at a flowing speed up to 1 m/s. Then, we employ machine learning algorithms to e …
Specifically, we first image the erythrocytes and leukocytes sorted by acoustofluidic sorting chip with different acoustic wave powers and f …
In-duct grating-like dielectric barrier discharge system for air disinfection.
Zhang L, Guo Y, Chang X, Yao Z, Wei X, Feng Z, Zhang D, Zhou Q, Wang X, Luo H. Zhang L, et al. J Hazard Mater. 2022 Aug 5;435:129075. doi: 10.1016/j.jhazmat.2022.129075. Epub 2022 May 6. J Hazard Mater. 2022. PMID: 35650753 Free PMC article.
Decreased airflow rates boosted the efficiency, which reached 99.8% at the velocity of 0.5 m/s with an aerosol residence time of ~3.6 ms. Increasing humidity (relative humidity (RH)=20-60%) contributed to inactivation efficacy, while high humidity (RH=70%-90%) led t …
Decreased airflow rates boosted the efficiency, which reached 99.8% at the velocity of 0.5 m/s with an aerosol residence time …
Strolling in Room-Scale VR: Hex-Core-MK1 Omnidirectional Treadmill.
Wang Z, Liu C, Chen J, Yao Y, Fang D, Shi Z, Yan R, Wang Y, Zhang K, Wang H, Wei H. Wang Z, et al. IEEE Trans Vis Comput Graph. 2023 Dec;29(12):5538-5555. doi: 10.1109/TVCG.2022.3216211. Epub 2023 Nov 10. IEEE Trans Vis Comput Graph. 2023. PMID: 36264727
The experiments show that HCMK1 can deliver a starting acceleration of 16.00 m/s (2) and a braking acceleration of 30.00 m/s (2)....
The experiments show that HCMK1 can deliver a starting acceleration of 16.00 m/s (2) and a braking acceleration of 30.00 m …
Typing of acute leukemia by intelligent optical time-stretch imaging flow cytometry on a chip.
Weng Y, Shen H, Mei L, Liu L, Yao Y, Li R, Wei S, Yan R, Ruan X, Wang D, Wei Y, Deng Y, Zhou Y, Xiao T, Goda K, Liu S, Zhou F, Lei C. Weng Y, et al. Lab Chip. 2023 Mar 14;23(6):1703-1712. doi: 10.1039/d2lc01048h. Lab Chip. 2023. PMID: 36799214
Specifically, we employ OTS microscopy to capture the images of cells in clinical bone marrow samples with a spatial resolution of 780 nm at a high flowing speed of 1 m s(-1) in a label-free manner. Then, to show the clinical utility of our method for which the feat …
Specifically, we employ OTS microscopy to capture the images of cells in clinical bone marrow samples with a spatial resolution of 780 nm at …
Prognostic value of the dynamic hepatorenal function on intermediate-term mortality in TAVI patients with survival to discharge.
Yao Y, He J, Xiong T, Chen F, Ou Y, Li Y, Liu Q, Zhu Z, Zhang Y, Yang H, Liang Y, Wei X, Li X, Peng Y, Wei J, He S, Li Q, Chen Y, Meng W, Chen G, Zhou W, Zheng M, Zhou X, Chen M, Feng Y. Yao Y, et al. Clin Cardiol. 2023 Jan;46(1):84-91. doi: 10.1002/clc.23940. Epub 2022 Nov 30. Clin Cardiol. 2023. PMID: 36448412 Free PMC article.
Factors associated with reversible MELD-XI scores improvement were low baseline MELD-XI scores (12.00, odds ratio [OR]: 2.02 [1.04-3.94], p = .04), high aortic valve peak velocity (5 m/s, OR: 2.17 [1.11-4.24], p = .02), and low body mass index (25 kg/m(2) , OR: 2.73 …
Factors associated with reversible MELD-XI scores improvement were low baseline MELD-XI scores (12.00, odds ratio [OR]: 2.02 [1.04-3.94], p …
13 results