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Locus coeruleus: a new look at the blue spot.

Poe GR, Foote S, Eschenko O, Johansen JP, Bouret S, Aston-Jones G, Harley CW, Manahan-Vaughan D, Weinshenker D, Valentino R, Berridge C, Chandler DJ, Waterhouse B, Sara SJ. Poe GR, et al. Among authors: weinshenker d. Nat Rev Neurosci. 2020 Nov;21(11):644-659. doi: 10.1038/s41583-020-0360-9. Epub 2020 Sep 17. Nat Rev Neurosci. 2020. PMID: 32943779 Review.

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Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease.

Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT. Balu DT, et al. Among authors: weinshenker d. Neurobiol Dis. 2019 Oct;130:104511. doi: 10.1016/j.nbd.2019.104511. Epub 2019 Jun 15. Neurobiol Dis. 2019. PMID: 31212068 Free PMC article.

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Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease.

Rorabaugh JM, Chalermpalanupap T, Botz-Zapp CA, Fu VM, Lembeck NA, Cohen RM, Weinshenker D. Rorabaugh JM, et al. Among authors: weinshenker d. Brain. 2017 Nov 1;140(11):3023-3038. doi: 10.1093/brain/awx232. Brain. 2017. PMID: 29053824 Free PMC article.

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Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.

Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, Giasson BI, Joers V, Weinshenker D, Tansey MG. Butkovich LM, et al. Among authors: weinshenker d. J Neurosci. 2020 Sep 23;40(39):7559-7576. doi: 10.1523/JNEUROSCI.1468-19.2020. Epub 2020 Aug 31. J Neurosci. 2020. PMID: 32868457 Free PMC article.

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The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice.

Manvich DF, Webster KA, Foster SL, Farrell MS, Ritchie JC, Porter JH, Weinshenker D. Manvich DF, et al. Among authors: weinshenker d. Sci Rep. 2018 Mar 1;8(1):3840. doi: 10.1038/s41598-018-22116-z. Sci Rep. 2018. PMID: 29497149 Free PMC article.

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Selective D₂ and D₃ receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens.

Manvich DF, Petko AK, Branco RC, Foster SL, Porter-Stransky KA, Stout KA, Newman AH, Miller GW, Paladini CA, Weinshenker D. Manvich DF, et al. Among authors: weinshenker d. Neuropsychopharmacology. 2019 Jul;44(8):1445-1455. doi: 10.1038/s41386-019-0371-2. Epub 2019 Mar 16. Neuropsychopharmacology. 2019. PMID: 30879021 Free PMC article.

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Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.

Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D. Chalermpalanupap T, et al. Among authors: weinshenker d. J Neurosci. 2018 Jan 3;38(1):74-92. doi: 10.1523/JNEUROSCI.1483-17.2017. Epub 2017 Nov 13. J Neurosci. 2018. PMID: 29133432 Free PMC article.

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Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease.

Weinshenker D. Weinshenker D. Trends Neurosci. 2018 Apr;41(4):211-223. doi: 10.1016/j.tins.2018.01.010. Epub 2018 Feb 20. Trends Neurosci. 2018. PMID: 29475564 Free PMC article. Review.

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Vesicular monoamine transporter 2 mediates fear behavior in mice.

Branco RC, Burkett JP, Black CA, Winokur E, Ellsworth W, Dhamsania RK, Lohr KM, Schroeder JP, Weinshenker D, Jovanovic T, Miller GW. Branco RC, et al. Among authors: weinshenker d. Genes Brain Behav. 2020 Jun;19(5):e12634. doi: 10.1111/gbb.12634. Epub 2020 Jan 14. Genes Brain Behav. 2020. PMID: 31898856 Free PMC article.

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Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood.

Rowson SA, Bekhbat M, Kelly SD, Binder EB, Hyer MM, Shaw G, Bent MA, Hodes G, Tharp G, Weinshenker D, Qin Z, Neigh GN. Rowson SA, et al. Among authors: weinshenker d. Neuropsychopharmacology. 2019 Jun;44(7):1207-1215. doi: 10.1038/s41386-019-0321-z. Epub 2019 Jan 23. Neuropsychopharmacology. 2019. PMID: 30710108 Free PMC article.

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