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Year Number of Results
2011 1
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2013 5
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2018 3
2019 2
2021 1
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18 results
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Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis.
Rosa N, Ivanova H, Wagner LE 2nd, Kale J, La Rovere R, Welkenhuyzen K, Louros N, Karamanou S, Shabardina V, Lemmens I, Vandermarliere E, Hamada K, Ando H, Rousseau F, Schymkowitz J, Tavernier J, Mikoshiba K, Economou A, Andrews DW, Parys JB, Yule DI, Bultynck G. Rosa N, et al. Among authors: welkenhuyzen k. Cell Death Differ. 2022 Apr;29(4):788-805. doi: 10.1038/s41418-021-00894-w. Epub 2021 Nov 8. Cell Death Differ. 2022. PMID: 34750538 Free PMC article.
mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.
Decuypere JP, Kindt D, Luyten T, Welkenhuyzen K, Missiaen L, De Smedt H, Bultynck G, Parys JB. Decuypere JP, et al. Among authors: welkenhuyzen k. PLoS One. 2013;8(4):e61020. doi: 10.1371/journal.pone.0061020. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565295 Free PMC article.
Basal ryanodine receptor activity suppresses autophagic flux.
Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G. Vervliet T, et al. Among authors: welkenhuyzen k. Biochem Pharmacol. 2017 May 15;132:133-142. doi: 10.1016/j.bcp.2017.03.011. Epub 2017 Mar 18. Biochem Pharmacol. 2017. PMID: 28322744 Free article.
Resveratrol-induced autophagy is dependent on IP3Rs and on cytosolic Ca2.
Luyten T, Welkenhuyzen K, Roest G, Kania E, Wang L, Bittremieux M, Yule DI, Parys JB, Bultynck G. Luyten T, et al. Among authors: welkenhuyzen k. Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):947-956. doi: 10.1016/j.bbamcr.2017.02.013. Epub 2017 Feb 28. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28254579 Free article.
Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2.
Bittremieux M, La Rovere RM, Akl H, Martines C, Welkenhuyzen K, Dubron K, Baes M, Janssens A, Vandenberghe P, Laurenti L, Rietdorf K, Morciano G, Pinton P, Mikoshiba K, Bootman MD, Efremov DG, De Smedt H, Parys JB, Bultynck G. Bittremieux M, et al. Among authors: welkenhuyzen k. Cell Death Differ. 2019 Mar;26(3):531-547. doi: 10.1038/s41418-018-0142-3. Epub 2018 Jun 13. Cell Death Differ. 2019. PMID: 29899382 Free PMC article.
Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
Ivanova H, Wagner LE 2nd, Tanimura A, Vandermarliere E, Luyten T, Welkenhuyzen K, Alzayady KJ, Wang L, Hamada K, Mikoshiba K, De Smedt H, Martens L, Yule DI, Parys JB, Bultynck G. Ivanova H, et al. Among authors: welkenhuyzen k. Cell Mol Life Sci. 2019 Oct;76(19):3843-3859. doi: 10.1007/s00018-019-03091-8. Epub 2019 Apr 16. Cell Mol Life Sci. 2019. PMID: 30989245
Disrupted Ca2+ homeostasis and immunodeficiency in patients with functional IP3 receptor subtype 3 defects.
Neumann J, Van Nieuwenhove E, Terry LE, Staels F, Knebel TR, Welkenhuyzen K, Ahmadzadeh K, Baker MR, Gerbaux M, Willemsen M, Barber JS, Serysheva II, De Waele L, Vermeulen F, Schlenner S, Meyts I, Yule DI, Bultynck G, Schrijvers R, Humblet-Baron S, Liston A. Neumann J, et al. Among authors: welkenhuyzen k. Cell Mol Immunol. 2022 Oct 27. doi: 10.1038/s41423-022-00928-4. Online ahead of print. Cell Mol Immunol. 2022. PMID: 36302985
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G. Kiviluoto S, et al. Among authors: welkenhuyzen k. Cell Calcium. 2013 Sep;54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16. Cell Calcium. 2013. PMID: 23867001
18 results