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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 1
1989 1
1992 2
1995 1
1996 1
1997 4
1998 4
1999 3
2001 1
2002 4
2003 2
2004 1
2005 2
2006 2
2007 3
2008 4
2009 2
2010 4
2011 2
2012 1
2013 3
2016 1
2020 2
2021 2
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49 results
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Page 1
IRAK-4 inhibitors for inflammation.
Wang Z, Wesche H, Stevens T, Walker N, Yeh WC. Wang Z, et al. Among authors: wesche h. Curr Top Med Chem. 2009;9(8):724-37. doi: 10.2174/156802609789044407. Curr Top Med Chem. 2009. PMID: 19689377 Free PMC article. Review.
TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors.
Austin RJ, Lemon BD, Aaron WH, Barath M, Culp PA, DuBridge RB, Evnin LB, Jones A, Panchal A, Patnaik P, Ramakrishnan V, Rocha SS, Seto P, Sexton K, Strobel KL, Wall R, Yu S, Yu TZ, Law CL, Baeuerle PA, Wesche H. Austin RJ, et al. Among authors: wesche h. Mol Cancer Ther. 2021 Jan;20(1):109-120. doi: 10.1158/1535-7163.MCT-20-0061. Epub 2020 Nov 17. Mol Cancer Ther. 2021. PMID: 33203731 Free article.
Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors.
Molloy ME, Austin RJ, Lemon BD, Aaron WH, Ganti V, Jones A, Jones SD, Strobel KL, Patnaik P, Sexton K, Tatalick L, Yu TZ, Baeuerle PA, Law CL, Wesche H. Molloy ME, et al. Among authors: wesche h. Clin Cancer Res. 2021 Mar 1;27(5):1452-1462. doi: 10.1158/1078-0432.CCR-20-3392. Epub 2020 Dec 1. Clin Cancer Res. 2021. PMID: 33262134 Free article.
"Spirit" of high throughput screening.
Wesche H, Xiao SH, Young S. Wesche H, et al. Comb Chem High Throughput Screen. 2008 Mar;11(3):174. doi: 10.2174/138620708783877799. Comb Chem High Throughput Screen. 2008. PMID: 18336210 No abstract available.
High throughput screening for protein kinase inhibitors.
Wesche H, Xiao SH, Young SW. Wesche H, et al. Comb Chem High Throughput Screen. 2005 Mar;8(2):181-95. doi: 10.2174/1386207053258514. Comb Chem High Throughput Screen. 2005. PMID: 15777182 Review.
Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
Gustin DJ, Li Y, Brown ML, Min X, Schmitt MJ, Wanska M, Wang X, Connors R, Johnstone S, Cardozo M, Cheng AC, Jeffries S, Franks B, Li S, Shen S, Wong M, Wesche H, Xu G, Carlson TJ, Plant M, Morgenstern K, Rex K, Schmitt J, Coxon A, Walker N, Kayser F, Wang Z. Gustin DJ, et al. Among authors: wesche h. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16. doi: 10.1016/j.bmcl.2013.06.030. Epub 2013 Jun 20. Bioorg Med Chem Lett. 2013. PMID: 23845219
Sphingosine kinase activity is not required for tumor cell viability.
Rex K, Jeffries S, Brown ML, Carlson T, Coxon A, Fajardo F, Frank B, Gustin D, Kamb A, Kassner PD, Li S, Li Y, Morgenstern K, Plant M, Quon K, Ruefli-Brasse A, Schmidt J, Swearingen E, Walker N, Wang Z, Watson JE, Wickramasinghe D, Wong M, Xu G, Wesche H. Rex K, et al. Among authors: wesche h. PLoS One. 2013 Jul 5;8(7):e68328. doi: 10.1371/journal.pone.0068328. Print 2013. PLoS One. 2013. PMID: 23861887 Free PMC article.
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