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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 8
1991 8
1992 2
1993 2
1994 2
1995 4
1996 2
1997 1
1998 6
1999 6
2000 9
2001 7
2002 3
2003 8
2004 3
2005 2
2006 6
2007 8
2008 7
2009 1
2010 2
2011 2
2012 2
2013 10
2014 11
2015 9
2016 9
2017 9
2018 7
2019 6
2020 8
2021 10
2022 5
2023 0
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Search Results

178 results
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Page 1
Factor XIa Inhibitors as New Anticoagulants.
Quan ML, Pinto DJP, Smallheer JM, Ewing WR, Rossi KA, Luettgen JM, Seiffert DA, Wexler RR. Quan ML, et al. Among authors: wexler rr. J Med Chem. 2018 Sep 13;61(17):7425-7447. doi: 10.1021/acs.jmedchem.8b00173. Epub 2018 May 18. J Med Chem. 2018. PMID: 29775297 Review.
Potent Triazolopyridine Myeloperoxidase Inhibitors.
Wurtz NR, Viet A, Shaw SA, Dilger A, Valente MN, Khan JA, Jusuf S, Narayanan R, Fernando G, Lo F, Liu X, Locke GA, Kopcho L, Abell LM, Sleph P, Basso M, Zhao L, Wexler RR, Duclos F, Kick EK. Wurtz NR, et al. Among authors: wexler rr. ACS Med Chem Lett. 2018 Nov 1;9(12):1175-1180. doi: 10.1021/acsmedchemlett.8b00308. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613322 Free PMC article.
Macrocyclic factor XIa inhibitors.
Wang C, Corte JR, Rossi KA, Bozarth JM, Wu Y, Sheriff S, Myers JE Jr, Luettgen JM, Seiffert DA, Wexler RR, Quan ML. Wang C, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4056-4060. doi: 10.1016/j.bmcl.2017.07.048. Epub 2017 Jul 25. Bioorg Med Chem Lett. 2017. PMID: 28780160
Design and preparation of N-linked hydroxypyridine-based APJ agonists.
Richter JM, Alex Bates J, Gargalovic P, Onorato JM, Generaux C, Wang T, Gordon DA, Wexler RR, Finlay HJ. Richter JM, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2022 Oct 1;73:128882. doi: 10.1016/j.bmcl.2022.128882. Epub 2022 Jul 8. Bioorg Med Chem Lett. 2022. PMID: 35817293
Factor Xa inhibitors: next-generation antithrombotic agents.
Pinto DJ, Smallheer JM, Cheney DL, Knabb RM, Wexler RR. Pinto DJ, et al. Among authors: wexler rr. J Med Chem. 2010 Sep 9;53(17):6243-74. doi: 10.1021/jm100146h. J Med Chem. 2010. PMID: 20503967 Review. No abstract available.
Neutral macrocyclic factor VIIa inhibitors.
Wurtz NR, Parkhurst BL, DeLucca I, Glunz PW, Jiang W, Zhang X, Cheney DL, Bozarth JM, Rendina AR, Wei A, Harper T, Luettgen JM, Wu Y, Wong PC, Seiffert DA, Wexler RR, Priestley ES. Wurtz NR, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2650-2654. doi: 10.1016/j.bmcl.2017.04.008. Epub 2017 Apr 19. Bioorg Med Chem Lett. 2017. PMID: 28460818
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists.
Wurtz NR, Johnson JA, Viet A, Shirude PS, Baligar V, Madduri S, Cheney DL, Park H, Lupisella JA, Hsu MY, Abousleiman M, Galella MA, Aulakh D, Dierks EA, Garcia RA, Ostrowski J, Kick EK, Wexler RR. Wurtz NR, et al. Among authors: wexler rr. ACS Med Chem Lett. 2022 May 25;13(6):943-948. doi: 10.1021/acsmedchemlett.2c00079. eCollection 2022 Jun 9. ACS Med Chem Lett. 2022. PMID: 35707160
Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Meng W, Adam LP, Behnia K, Zhao L, Yang R, Kopcho LM, Locke GA, Taylor DS, Yin X, Wexler RR, Finlay H. Meng W, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126673. doi: 10.1016/j.bmcl.2019.126673. Epub 2019 Sep 6. Bioorg Med Chem Lett. 2019. PMID: 31519373
Nonpeptide angiotensin II receptor antagonists.
Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Wexler RR, Johnson AL. Timmermans PB, et al. Among authors: wexler rr. Am J Hypertens. 1990 Aug;3(8 Pt 1):599-604. doi: 10.1093/ajh/3.8.599. Am J Hypertens. 1990. PMID: 2222950 Review.
178 results