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Predictive In Vitro-In Vivo Extrapolation for Time Dependent Inhibition of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and CYP2D6 Using Pooled Human Hepatocytes, Human Liver Microsomes, and a Simple Mechanistic Static Model.
Ramsden D, Perloff ES, Whitcher-Johnstone A, Ho T, Patel R, Kozminski KD, Fullenwider CL, Zhang JG. Ramsden D, et al. Among authors: whitcher johnstone a. Drug Metab Dispos. 2022 Feb;50(2):114-127. doi: 10.1124/dmd.121.000718. Epub 2021 Nov 17. Drug Metab Dispos. 2022. PMID: 34789487