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87 results

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Page 1
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I. Shin D, et al. Among authors: widera m. Nature. 2020 Nov;587(7835):657-662. doi: 10.1038/s41586-020-2601-5. Epub 2020 Jul 29. Nature. 2020. PMID: 32726803 Free PMC article.
Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients.
Enssle JC, Campe J, Moter A, Voit I, Gessner A, Yu W, Wolf S, Steffen B, Serve H, Bremm M, Huenecke S, Lohoff M, Vehreschild M, Rabenau HF, Widera M, Ciesek S, Oellerich T, Imkeller K, Rieger MA, von Metzler I, Ullrich E. Enssle JC, et al. Among authors: widera m. Leukemia. 2024 Jan;38(1):168-180. doi: 10.1038/s41375-023-02070-0. Epub 2023 Dec 4. Leukemia. 2024. PMID: 38049509 Free PMC article.
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. Barut GT, et al. Among authors: widera m. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. Nat Commun. 2022. PMID: 36207334 Free PMC article.
SARS-CoV-2-specific cellular and humoral immunity after bivalent BA.4/5 COVID-19-vaccination in previously infected and non-infected individuals.
Urschel R, Bronder S, Klemis V, Marx S, Hielscher F, Abu-Omar A, Guckelmus C, Schneitler S, Baum C, Becker SL, Gärtner BC, Sester U, Martinez L, Widera M, Schmidt T, Sester M. Urschel R, et al. Among authors: widera m. Nat Commun. 2024 Apr 9;15(1):3077. doi: 10.1038/s41467-024-47429-8. Nat Commun. 2024. PMID: 38594497 Free PMC article.
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B, Miskey C, Gömer A, Kleinert RDV, Ibanez SC, Eberle R, Ebenig A, Postmus D, Nocke MK, Herrmann M, Itotia TK, Herrmann ST, Heinen N, Höck S, Hastert FD, von Rhein C, Schürmann C, Li X, van Zandbergen G, Widera M, Ciesek S, Schnierle BS, Tarr AW, Steinmann E, Goffinet C, Pfaender S, Locker JK, Mühlebach MD, Todt D, Brown RJP. Qu B, et al. Among authors: widera m. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2407437121. doi: 10.1073/pnas.2407437121. Epub 2024 May 30. Proc Natl Acad Sci U S A. 2024. PMID: 38814864 Free PMC article.
Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models.
Corleis B, Hoffmann D, Rauch S, Fricke C, Roth N, Gergen J, Kovacikova K, Schlottau K, Halwe NJ, Ulrich L, Schön J, Wernike K, Widera M, Ciesek S, Mueller SO, Mettenleiter TC, Maione D, Petsch B, Beer M, Dorhoi A. Corleis B, et al. Among authors: widera m. Nat Commun. 2023 Feb 13;14(1):816. doi: 10.1038/s41467-023-36110-1. Nat Commun. 2023. PMID: 36781853 Free PMC article.
Hypoxia-altered cholesterol homeostasis enhances the expression of interferon-stimulated genes upon SARS-CoV-2 infections in monocytes.
Bauer R, Meyer SP, Raue R, Palmer MA, Guerrero Ruiz VM, Cardamone G, Rösser S, Heffels M, Roesmann F, Wilhelm A, Lütjohann D, Zarnack K, Fuhrmann DC, Widera M, Schmid T, Brüne B. Bauer R, et al. Among authors: widera m. Front Immunol. 2023 Jun 12;14:1121864. doi: 10.3389/fimmu.2023.1121864. eCollection 2023. Front Immunol. 2023. PMID: 37377965 Free PMC article.
A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants.
Metzdorf K, Jacobsen H, Kim Y, Teixeira Alves LG, Kulkarni U, Brdovčak MC, Materljan J, Eschke K, Chaudhry MZ, Hoffmann M, Bertoglio F, Ruschig M, Hust M, Šustić M, Krmpotić A, Jonjić S, Widera M, Ciesek S, Pöhlmann S, Landthaler M, Čičin-Šain L. Metzdorf K, et al. Among authors: widera m. Front Immunol. 2024 Jul 25;15:1383086. doi: 10.3389/fimmu.2024.1383086. eCollection 2024. Front Immunol. 2024. PMID: 39119342 Free PMC article.
87 results