Wikel JH[au] - Search Results

Year	Number of Results
1980	1
1984	1
1989	1
1992	1
1994	1
1997	1
1998	2
1999	5
2000	3
2001	1
2002	3
2003	1
2004	1
2006	1
2016	1
2018	1
2022	0

1

Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization.

Sardar Pasha SPB, Sishtla K, Sulaiman RS, Park B, Shetty T, Shah F, Fishel ML, Wikel JH, Kelley MR, Corson TW. Sardar Pasha SPB, et al. Among authors: wikel jh. J Pharmacol Exp Ther. 2018 Oct;367(1):108-118. doi: 10.1124/jpet.118.248088. Epub 2018 Aug 3. J Pharmacol Exp Ther. 2018. PMID: 30076264 Free PMC article.

2

Progress in predicting human ADME parameters in silico.

Ekins S, Waller CL, Swaan PW, Cruciani G, Wrighton SA, Wikel JH. Ekins S, et al. Among authors: wikel jh. J Pharmacol Toxicol Methods. 2000 Jul-Aug;44(1):251-72. doi: 10.1016/s1056-8719(00)00109-x. J Pharmacol Toxicol Methods. 2000. PMID: 11274894 Review.

3

1,2-Dibenzamidobenzene inhibitors of human factor Xa.

Herron DK, Goodson T Jr, Wiley MR, Weir LC, Kyle JA, Yee YK, Tebbe AL, Tinsley JM, Mendel D, Masters JJ, Franciskovich JB, Sawyer JS, Beight DW, Ratz AM, Milot G, Hall SE, Klimkowski VJ, Wikel JH, Eastwood BJ, Towner RD, Gifford-Moore DS, Craft TJ, Smith GF. Herron DK, et al. Among authors: wikel jh. J Med Chem. 2000 Mar 9;43(5):859-72. doi: 10.1021/jm990326m. J Med Chem. 2000. PMID: 10715153

4

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy.

Kelley MR, Wikel JH, Guo C, Pollok KE, Bailey BJ, Wireman R, Fishel ML, Vasko MR. Kelley MR, et al. Among authors: wikel jh. J Pharmacol Exp Ther. 2016 Nov;359(2):300-309. doi: 10.1124/jpet.116.235283. Epub 2016 Sep 8. J Pharmacol Exp Ther. 2016. PMID: 27608656 Free PMC article.

5

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.

Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Ekins S, et al. Among authors: wikel jh. Mol Pharmacol. 2002 May;61(5):964-73. doi: 10.1124/mol.61.5.964. Mol Pharmacol. 2002. PMID: 11961113

6

Acyl sulfonamide anti-proliferatives: benzene substituent structure-activity relationships for a novel class of antitumor agents.

Lobb KL, Hipskind PA, Aikins JA, Alvarez E, Cheung YY, Considine EL, De Dios A, Durst GL, Ferritto R, Grossman CS, Giera DD, Hollister BA, Huang Z, Iversen PW, Law KL, Li T, Lin HS, Lopez B, Lopez JE, Cabrejas LM, McCann DJ, Molero V, Reilly JE, Richett ME, Shih C, Teicher B, Wikel JH, White WT, Mader MM. Lobb KL, et al. Among authors: wikel jh. J Med Chem. 2004 Oct 21;47(22):5367-80. doi: 10.1021/jm030594r. J Med Chem. 2004. PMID: 15481975

7

Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.

Bednarczyk D, Ekins S, Wikel JH, Wright SH. Bednarczyk D, et al. Among authors: wikel jh. Mol Pharmacol. 2003 Mar;63(3):489-98. doi: 10.1124/mol.63.3.489. Mol Pharmacol. 2003. PMID: 12606755

8

Three-dimensional quantitative structure activity relationship analyses of substrates for CYP2B6.

Ekins S, Bravi G, Ring BJ, Gillespie TA, Gillespie JS, Vandenbranden M, Wrighton SA, Wikel JH. Ekins S, et al. Among authors: wikel jh. J Pharmacol Exp Ther. 1999 Jan;288(1):21-9. J Pharmacol Exp Ther. 1999. PMID: 9862748

9

Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates.

Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Ekins S, et al. Among authors: wikel jh. Mol Pharmacol. 2002 May;61(5):974-81. doi: 10.1124/mol.61.5.974. Mol Pharmacol. 2002. PMID: 11961114

10

Depletion of cardiac norepinephrine in rats and mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Fuller RW, Hahn RA, Snoddy HD, Wikel JH. Fuller RW, et al. Among authors: wikel jh. Biochem Pharmacol. 1984 Oct 1;33(19):2957-60. doi: 10.1016/0006-2952(84)90593-8. Biochem Pharmacol. 1984. PMID: 6333240

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