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Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements.
Adv Exp Med Biol. 1998;436:169-77.
Adv Exp Med Biol. 1998.
PMID: 9561215
Review.
No abstract available.
Crystal structure of the CCTgamma apical domain: implications for substrate binding to the eukaryotic cytosolic chaperonin.
Pappenberger G, Wilsher JA, Roe SM, Counsell DJ, Willison KR, Pearl LH.
Pappenberger G, et al. Among authors: wilsher ja.
J Mol Biol. 2002 May 17;318(5):1367-79. doi: 10.1016/s0022-2836(02)00190-0.
J Mol Biol. 2002.
PMID: 12083524
Item in Clipboard
TCL1 is activated by chromosomal rearrangement or by hypomethylation.
Yuille MR, Condie A, Stone EM, Wilsher J, Bradshaw PS, Brooks L, Catovsky D.
Yuille MR, et al. Among authors: wilsher j.
Genes Chromosomes Cancer. 2001 Apr;30(4):336-41. doi: 10.1002/gcc.1099.
Genes Chromosomes Cancer. 2001.
PMID: 11241786
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Cystic fibrosis mortality and survival in the UK: 1947-2003.
Dodge JA, Lewis PA, Stanton M, Wilsher J.
Dodge JA, et al. Among authors: wilsher j.
Eur Respir J. 2007 Mar;29(3):522-6. doi: 10.1183/09031936.00099506. Epub 2006 Dec 20.
Eur Respir J. 2007.
PMID: 17182652
Free article.
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Protein engineering loops in aspartic proteinases: site-directed mutagenesis, biochemical characterization and X-ray analysis of chymosin with a replaced loop from rhizopuspepsin.
Nugent PG, Albert A, Orprayoon P, Wilsher J, Pitts JE, Blundell TL, Dhanaraj V.
Nugent PG, et al. Among authors: wilsher j.
Protein Eng. 1996 Oct;9(10):885-93. doi: 10.1093/protein/9.10.885.
Protein Eng. 1996.
PMID: 8931128
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Mutagenesis, biochemical characterization and X-ray structural analysis of point mutants of bovine chymosin.
Williams MG, Wilsher J, Nugent P, Mills A, Dhanaraj V, Fabry M, Sedlácek J, Uusitalo JM, Penttila ME, Pitts JE, Blundell TL.
Williams MG, et al. Among authors: wilsher j.
Protein Eng. 1997 Sep;10(9):991-7. doi: 10.1093/protein/10.9.991.
Protein Eng. 1997.
PMID: 9464563
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