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The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Lieu T, Jayaweera G, Zhao P, Poole DP, Jensen D, Grace M, McIntyre P, Bron R, Wilson YM, Krappitz M, Haerteis S, Korbmacher C, Steinhoff MS, Nassini R, Materazzi S, Geppetti P, Corvera CU, Bunnett NW. Lieu T, et al. Among authors: wilson ym. Gastroenterology. 2014 Dec;147(6):1417-28. doi: 10.1053/j.gastro.2014.08.042. Epub 2014 Sep 3. Gastroenterology. 2014. PMID: 25194674 Free PMC article.
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