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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1984 1
1985 1
1986 2
1987 3
1988 7
1989 2
1990 1
1991 3
1992 1
1993 3
1994 5
1995 5
1996 6
1997 10
1998 6
1999 2
2000 3
2001 5
2002 4
2003 2
2004 3
2005 9
2006 8
2007 5
2009 3
2011 5
2012 5
2014 3
2015 9
2016 7
2017 14
2018 8
2019 5
2020 5
2021 4
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158 results
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Page 1
SIRT1 is downregulated by autophagy in senescence and ageing.
Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, Johansen T, Dou Z, Berger SL. Xu C, et al. Among authors: winkler jd. Nat Cell Biol. 2020 Oct;22(10):1170-1179. doi: 10.1038/s41556-020-00579-5. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989246 Free PMC article.
Targeted protein degradation by PROTACs.
Neklesa TK, Winkler JD, Crews CM. Neklesa TK, et al. Among authors: winkler jd. Pharmacol Ther. 2017 Jun;174:138-144. doi: 10.1016/j.pharmthera.2017.02.027. Epub 2017 Feb 14. Pharmacol Ther. 2017. PMID: 28223226 Review.
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma.
Sharma G, Ojha R, Noguera-Ortega E, Rebecca VW, Attanasio J, Liu S, Piao S, Lee JJ, Nicastri MC, Harper SL, Ronghe A, Jain V, Winkler JD, Speicher DW, Mastio J, Gimotty PA, Xu X, Wherry EJ, Gabrilovich DI, Amaravadi RK. Sharma G, et al. Among authors: winkler jd. JCI Insight. 2020 Sep 3;5(17):e133225. doi: 10.1172/jci.insight.133225. JCI Insight. 2020. PMID: 32780726 Free PMC article.
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.
Lu J, Qian Y, Altieri M, Dong H, Wang J, Raina K, Hines J, Winkler JD, Crew AP, Coleman K, Crews CM. Lu J, et al. Among authors: winkler jd. Chem Biol. 2015 Jun 18;22(6):755-63. doi: 10.1016/j.chembiol.2015.05.009. Epub 2015 Jun 4. Chem Biol. 2015. PMID: 26051217 Free PMC article.
PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.
Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, Lee JJ, Schuchter LM, Xu X, Herlyn M, Marmorstein R, Gimotty PA, Speicher DW, Winkler JD, Amaravadi RK. Rebecca VW, et al. Among authors: winkler jd. Cancer Discov. 2019 Feb;9(2):220-229. doi: 10.1158/2159-8290.CD-18-0706. Epub 2018 Nov 15. Cancer Discov. 2019. PMID: 30442709 Free PMC article.
CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers.
Vijayaraghavan S, Karakas C, Doostan I, Chen X, Bui T, Yi M, Raghavendra AS, Zhao Y, Bashour SI, Ibrahim NK, Karuturi M, Wang J, Winkler JD, Amaravadi RK, Hunt KK, Tripathy D, Keyomarsi K. Vijayaraghavan S, et al. Among authors: winkler jd. Nat Commun. 2017 Jun 27;8:15916. doi: 10.1038/ncomms15916. Nat Commun. 2017. PMID: 28653662 Free PMC article.
Complex systems in metabolic engineering.
Winkler JD, Erickson K, Choudhury A, Halweg-Edwards AL, Gill RT. Winkler JD, et al. Curr Opin Biotechnol. 2015 Dec;36:107-14. doi: 10.1016/j.copbio.2015.08.002. Epub 2015 Aug 28. Curr Opin Biotechnol. 2015. PMID: 26319897 Review.
Gilbert Stork (1921-2017).
Nakamura E, Winkler JD, Aggarwal VK. Nakamura E, et al. Among authors: winkler jd. Angew Chem Int Ed Engl. 2018 Jan 2;57(1):36. doi: 10.1002/anie.201711474. Epub 2017 Nov 29. Angew Chem Int Ed Engl. 2018. PMID: 29193592
158 results
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