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Year Number of Results
2012 2
2013 4
2014 1
2016 1
2017 1
2018 2
2020 2
2022 5
2023 0

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16 results

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Page 1
Renal transporters in drug development.
Morrissey KM, Stocker SL, Wittwer MB, Xu L, Giacomini KM. Morrissey KM, et al. Among authors: wittwer mb. Annu Rev Pharmacol Toxicol. 2013;53:503-29. doi: 10.1146/annurev-pharmtox-011112-140317. Epub 2012 Nov 8. Annu Rev Pharmacol Toxicol. 2013. PMID: 23140242 Review.
Fundamental aspects of DMPK optimization of targeted protein degraders.
Cantrill C, Chaturvedi P, Rynn C, Petrig Schaffland J, Walter I, Wittwer MB. Cantrill C, et al. Among authors: wittwer mb. Drug Discov Today. 2020 Jun;25(6):969-982. doi: 10.1016/j.drudis.2020.03.012. Epub 2020 Apr 13. Drug Discov Today. 2020. PMID: 32298797 Review.
Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance.
Zamek-Gliszczynski MJ, Taub ME, Chothe PP, Chu X, Giacomini KM, Kim RB, Ray AS, Stocker SL, Unadkat JD, Wittwer MB, Xia C, Yee SW, Zhang L, Zhang Y; International Transporter Consortium. Zamek-Gliszczynski MJ, et al. Among authors: wittwer mb. Clin Pharmacol Ther. 2018 Nov;104(5):890-899. doi: 10.1002/cpt.1112. Epub 2018 Aug 8. Clin Pharmacol Ther. 2018. PMID: 30091177 Free PMC article. Review.
Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance.
Zamek-Gliszczynski MJ, Sangha V, Shen H, Feng B, Wittwer MB, Varma MVS, Liang X, Sugiyama Y, Zhang L, Bendayan R; International Transporter Consortium. Zamek-Gliszczynski MJ, et al. Among authors: wittwer mb. Clin Pharmacol Ther. 2022 Sep;112(3):485-500. doi: 10.1002/cpt.2644. Epub 2022 Jun 29. Clin Pharmacol Ther. 2022. PMID: 35561119 Review.
Chemical development of intracellular protein heterodimerizers.
Erhart D, Zimmermann M, Jacques O, Wittwer MB, Ernst B, Constable E, Zvelebil M, Beaufils F, Wymann MP. Erhart D, et al. Among authors: wittwer mb. Chem Biol. 2013 Apr 18;20(4):549-57. doi: 10.1016/j.chembiol.2013.03.010. Chem Biol. 2013. PMID: 23601644
Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.
He Y, Gobbi LC, Herde AM, Rombach D, Ritter M, Kuhn B, Wittwer MB, Heer D, Hornsperger B, Bell C, O'Hara F, Benz J, Honer M, Keller C, Collin L, Richter H, Schibli R, Grether U, Mu L. He Y, et al. Among authors: wittwer mb. Nucl Med Biol. 2022 May-Jun;108-109:24-32. doi: 10.1016/j.nucmedbio.2022.02.002. Epub 2022 Feb 23. Nucl Med Biol. 2022. PMID: 35248850 Free article.
Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain.
He Y, Grether U, Taddio MF, Meier C, Keller C, Edelmann MR, Honer M, Huber S, Wittwer MB, Heer D, Richter H, Collin L, Hug MN, Hilbert M, Postmus AGJ, Stevens AF, van der Stelt M, Krämer SD, Schibli R, Mu L, Gobbi LC. He Y, et al. Among authors: wittwer mb. Eur J Med Chem. 2022 Dec 5;243:114750. doi: 10.1016/j.ejmech.2022.114750. Epub 2022 Sep 9. Eur J Med Chem. 2022. PMID: 36137365 Free article.
16 results