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Page 1
MeCP2 links heterochromatin condensates and neurodevelopmental disease.
Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, Svoboda DS, Wogram E, Lee TI, Jaenisch R, Young RA. Li CH, et al. Among authors: wogram e. Nature. 2020 Oct;586(7829):440-444. doi: 10.1038/s41586-020-2574-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32698189 Free PMC article.
Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases.
Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, Lauffenburger DA, Trumper D, Jaenisch R, Griffith LG. Trapecar M, et al. Among authors: wogram e. Sci Adv. 2021 Jan 29;7(5):eabd1707. doi: 10.1126/sciadv.abd1707. Print 2021 Jan. Sci Adv. 2021. PMID: 33514545 Free PMC article.
APOE set the microglia free.
Wogram E, Prinz M. Wogram E, et al. Nat Immunol. 2023 Nov;24(11):1790-1791. doi: 10.1038/s41590-023-01651-6. Nat Immunol. 2023. PMID: 37872317 No abstract available.
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Linnerbauer M, Lößlein L, Vandrey O, Peter A, Han Y, Tsaktanis T, Wogram E, Needhamsen M, Kular L, Nagel L, Zissler J, Andert M, Meszaros L, Hanspach J, Zuber F, Naumann UJ, Diebold M, Wheeler MA, Beyer T, Nirschl L, Cirac A, Laun FB, Günther C, Winkler J, Bäuerle T, Jagodic M, Hemmer B, Prinz M, Quintana FJ, Rothhammer V. Linnerbauer M, et al. Among authors: wogram e. Nat Immunol. 2024 Mar;25(3):432-447. doi: 10.1038/s41590-024-01756-6. Epub 2024 Feb 26. Nat Immunol. 2024. PMID: 38409259 Free PMC article.
Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes.
Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R. Wogram E, et al. Immunity. 2024 Sep 10;57(9):2216-2231.e11. doi: 10.1016/j.immuni.2024.07.019. Epub 2024 Aug 15. Immunity. 2024. PMID: 39151426