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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2003 2
2004 1
2005 1
2006 2
2007 4
2009 2
2010 5
2011 5
2012 8
2013 9
2014 2
2015 2
2016 10
2017 8
2018 13
2019 7
2020 14
2021 14
2022 9
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108 results
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Page 1
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms.
Josephs TM, Belousoff MJ, Liang YL, Piper SJ, Cao J, Garama DJ, Leach K, Gregory KJ, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. Josephs TM, et al. Among authors: wootten d. Science. 2021 Apr 9;372(6538):eabf7258. doi: 10.1126/science.abf7258. Epub 2021 Feb 18. Science. 2021. PMID: 33602864
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: wootten d. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.
Evolving cryo-EM structural approaches for GPCR drug discovery.
Zhang X, Johnson RM, Drulyte I, Yu L, Kotecha A, Danev R, Wootten D, Sexton PM, Belousoff MJ. Zhang X, et al. Among authors: wootten d. Structure. 2021 Sep 2;29(9):963-974.e6. doi: 10.1016/j.str.2021.04.008. Epub 2021 May 5. Structure. 2021. PMID: 33957078 Free article.
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Zhang X, et al. Among authors: wootten d. Mol Cell. 2020 Nov 5;80(3):485-500.e7. doi: 10.1016/j.molcel.2020.09.020. Epub 2020 Oct 6. Mol Cell. 2020. PMID: 33027691 Free article.
RAMPs and CGRP receptors.
Barwell J, Wootten D, Simms J, Hay DL, Poyner DR. Barwell J, et al. Among authors: wootten d. Adv Exp Med Biol. 2012;744:13-24. doi: 10.1007/978-1-4614-2364-5_2. Adv Exp Med Biol. 2012. PMID: 22434104 Review.
Rules of Engagement: GPCRs and G Proteins.
Glukhova A, Draper-Joyce CJ, Sunahara RK, Christopoulos A, Wootten D, Sexton PM. Glukhova A, et al. Among authors: wootten d. ACS Pharmacol Transl Sci. 2018 Sep 7;1(2):73-83. doi: 10.1021/acsptsci.8b00026. eCollection 2018 Nov 9. ACS Pharmacol Transl Sci. 2018. PMID: 32219204 Free PMC article. Review.
Chemical Synthesis and Characterization of a Nonfibrillating Glycoglucagon.
Liu M, Zhao P, Uddin MH, Li W, Lin F, Chandrashekar C, Nishiuchi Y, Kajihara Y, Forbes BE, Wootten D, Wade JD, Hossain MA. Liu M, et al. Among authors: wootten d. Bioconjug Chem. 2021 Oct 20;32(10):2148-2153. doi: 10.1021/acs.bioconjchem.1c00419. Epub 2021 Sep 8. Bioconjug Chem. 2021. PMID: 34494823
Routine sub-2.5 Å cryo-EM structure determination of GPCRs.
Danev R, Belousoff M, Liang YL, Zhang X, Eisenstein F, Wootten D, Sexton PM. Danev R, et al. Among authors: wootten d. Nat Commun. 2021 Jul 15;12(1):4333. doi: 10.1038/s41467-021-24650-3. Nat Commun. 2021. PMID: 34267200 Free PMC article.
108 results