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Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study.
Khoo SH, Fitzgerald R, Fletcher T, Ewings S, Jaki T, Lyon R, Downs N, Walker L, Tansley-Hancock O, Greenhalf W, Woods C, Reynolds H, Marwood E, Mozgunov P, Adams E, Bullock K, Holman W, Bula MD, Gibney JL, Saunders G, Corkhill A, Hale C, Thorne K, Chiong J, Condie S, Pertinez H, Painter W, Wrixon E, Johnson L, Yeats S, Mallard K, Radford M, Fines K, Shaw V, Owen A, Lalloo DG, Jacobs M, Griffiths G. Khoo SH, et al. Among authors: wrixon e. J Antimicrob Chemother. 2021 Nov 12;76(12):3286-3295. doi: 10.1093/jac/dkab318. J Antimicrob Chemother. 2021. PMID: 34450619 Free PMC article. Clinical Trial.
Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial.
Willcox M, Simpson C, Wilding S, Stuart B, Soilemezi D, Whitehead A, Morgan A, Wrixon E, Zhu S, Yao G, Webley F, Yan R, Bostock J, Bell M, Griffiths G, Leydon G, Little P, Butler C, Hay AD, Moore M. Willcox M, et al. Among authors: wrixon e. BMC Complement Med Ther. 2021 Jan 29;21(1):48. doi: 10.1186/s12906-021-03206-4. BMC Complement Med Ther. 2021. PMID: 33514367 Free PMC article. Clinical Trial.
HATRIC: a study of Pelargonium sidoides root extract EPs®7630 (Kaloba®) for the treatment of acute cough due to lower respiratory tract infection in adults-study protocol for a double blind, placebo-controlled randomised feasibility trial.
Whitehead A, Simpson C, Willcox M, Webley F, Hay AD, Butler C, Yao L, Wrixon E, Bell M, Bostock J, Little P, Griffiths G, Moore M. Whitehead A, et al. Among authors: wrixon e. Pilot Feasibility Stud. 2019 Jul 31;5:98. doi: 10.1186/s40814-019-0478-6. eCollection 2019. Pilot Feasibility Stud. 2019. PMID: 31384480 Free PMC article.
AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trial.
Griffiths G, Fitzgerald R, Jaki T, Corkhill A, Marwood E, Reynolds H, Stanton L, Ewings S, Condie S, Wrixon E, Norton A, Radford M, Yeats S, Robertson J, Darby-Dowman R, Walker L, Khoo S; UK NIHR community. Griffiths G, et al. Among authors: wrixon e. Trials. 2020 Jun 19;21(1):544. doi: 10.1186/s13063-020-04473-1. Trials. 2020. PMID: 32560744 Free PMC article.