Wynant I[au] - Search Results

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Year	Number of Results
2014	1
2015	1
2016	1
2019	1
2020	2
2021	2
2022	0

Page 1

Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib.

De Zwart L, Snoeys J, Jacobs F, Li LY, Poggesi I, Verboven P, Goris I, Scheers E, Wynant I, Monshouwer M, Mamidi RNVS. De Zwart L, et al. Among authors: wynant i. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):1107-1118. doi: 10.1002/psp4.12682. Epub 2021 Aug 11. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34273250 Free PMC article.

Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor.

Scheers E, Borgmans C, Keung C, Bohets H, Wynant I, Poggesi I, Cuyckens F, Leclercq L, Mamidi RNVS. Scheers E, et al. Among authors: wynant i. Xenobiotica. 2021 Feb;51(2):177-193. doi: 10.1080/00498254.2020.1821123. Epub 2020 Sep 20. Xenobiotica. 2021. PMID: 32902324

Integrating Duodenal Sampling in a Human Mass Balance Study to Quantify the Elimination Pathways of JNJ-53718678, a Respiratory Syncytial Virus Fusion Protein Inhibitor.

Remmerie B, van den Boer M, Van Looy T, Wynant I, Rusch S, Huntjens D, De Meulder M, Stevens M. Remmerie B, et al. Among authors: wynant i. Adv Ther. 2020 Jan;37(1):578-591. doi: 10.1007/s12325-019-01162-7. Epub 2019 Dec 12. Adv Ther. 2020. PMID: 31832988

Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin.

De Jonghe S, Proctor J, Vinken P, Feyen B, Wynant I, Marien D, Geys H, Mamidi RN, Johnson MD. De Jonghe S, et al. Among authors: wynant i. Chem Biol Interact. 2014 Dec 5;224:1-12. doi: 10.1016/j.cbi.2014.09.018. Epub 2014 Oct 5. Chem Biol Interact. 2014. PMID: 25289773

Evaluation of the Pharmacokinetics and Renal Excretion of Simeprevir in Subjects with Renal Impairment.

Ouwerkerk-Mahadevan S, Beumont-Mauviel M, Mortier S, Peeters M, Verloes R, Truyers C, Mannens G, Wynant I, Simion A. Ouwerkerk-Mahadevan S, et al. Among authors: wynant i. Drugs R D. 2015 Sep;15(3):261-70. doi: 10.1007/s40268-015-0101-0. Drugs R D. 2015. PMID: 26248593 Free PMC article. Clinical Trial.

In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity.

Monbaliu J, Gonzalez M, Bernard A, Jiao J, Sensenhauser C, Snoeys J, Stieltjes H, Wynant I, Smit JW, Chien C. Monbaliu J, et al. Among authors: wynant i. Drug Metab Dispos. 2016 Oct;44(10):1682-91. doi: 10.1124/dmd.116.070672. Epub 2016 Aug 8. Drug Metab Dispos. 2016. PMID: 27504016

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