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Year Number of Results
1986 1
2001 1
2004 1
2011 4
2012 2
2014 1
2017 1
2019 2
2020 6
2021 10
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Page 1
Kinetic fingerprints differentiate the mechanisms of action of anti-AĪ² antibodies.
Linse S, Scheidt T, Bernfur K, Vendruscolo M, Dobson CM, Cohen SIA, Sileikis E, Lundqvist M, Qian F, O'Malley T, Bussiere T, Weinreb PH, Xu CK, Meisl G, Devenish SRA, Knowles TPJ, Hansson O. Linse S, et al. Among authors: xu ck. Nat Struct Mol Biol. 2020 Dec;27(12):1125-1133. doi: 10.1038/s41594-020-0505-6. Epub 2020 Sep 28. Nat Struct Mol Biol. 2020. PMID: 32989305
Interactions of Ī±-synuclein oligomers with lipid membranes.
Musteikytė G, Jayaram AK, Xu CK, Vendruscolo M, Krainer G, Knowles TPJ. Musteikytė G, et al. Among authors: xu ck. Biochim Biophys Acta Biomembr. 2021 Apr 1;1863(4):183536. doi: 10.1016/j.bbamem.2020.183536. Epub 2020 Dec 26. Biochim Biophys Acta Biomembr. 2021. PMID: 33373595 Review.
Trodusquemine enhances AĪ²42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.
Limbocker R, Chia S, Ruggeri FS, Perni M, Cascella R, Heller GT, Meisl G, Mannini B, Habchi J, Michaels TCT, Challa PK, Ahn M, Casford ST, Fernando N, Xu CK, Kloss ND, Cohen SIA, Kumita JR, Cecchi C, Zasloff M, Linse S, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM. Limbocker R, et al. Among authors: xu ck. Nat Commun. 2019 Jan 15;10(1):225. doi: 10.1038/s41467-018-07699-5. Nat Commun. 2019. PMID: 30644384 Free PMC article.
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.
Limbocker R, Mannini B, Ruggeri FS, Cascella R, Xu CK, Perni M, Chia S, Chen SW, Habchi J, Bigi A, Kreiser RP, Wright AK, Albright JA, Kartanas T, Kumita JR, Cremades N, Zasloff M, Cecchi C, Knowles TPJ, Chiti F, Vendruscolo M, Dobson CM. Limbocker R, et al. Among authors: xu ck. Commun Biol. 2020 Aug 13;3(1):435. doi: 10.1038/s42003-020-01140-8. Commun Biol. 2020. PMID: 32792544 Free PMC article.
A dopamine metabolite stabilizes neurotoxic amyloid-Ī² oligomers.
Cataldi R, Chia S, Pisani K, Ruggeri FS, Xu CK, Å neideris T, Perni M, Sarwat S, Joshi P, Kumita JR, Linse S, Habchi J, Knowles TPJ, Mannini B, Dobson CM, Vendruscolo M. Cataldi R, et al. Among authors: xu ck. Commun Biol. 2021 Jan 4;4(1):19. doi: 10.1038/s42003-020-01490-3. Commun Biol. 2021. PMID: 33398040 Free PMC article.
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