Pro-neurocognitive and anti-sarcopenic benefits of one-year metformin therapy in ovariectomized aged mice.
Zakeri M, Fatemi I, Kaeidi A, Zakeri MA, Hakimizadeh E, Hassanipour M, Rahmani M, Hassanshahi J, Ayoobi F, Allahtavakoli M.
Zakeri M, et al.
Clin Exp Pharmacol Physiol. 2019 Dec;46(12):1133-1140. doi: 10.1111/1440-1681.13149. Epub 2019 Aug 30.
Clin Exp Pharmacol Physiol. 2019.
PMID: 31357227
The anxiety-like behavior, working memory, and physical strength were measured through elevated plus maze, Y-maze, vertical grid holding, and the obligatory swimming capacity tests. Brains were harvested to measure brain-derived neurotrophic factor (BDNF) level. ...
The anxiety-like behavior, working memory, and physical strength were measured through elevated plus maze, Y-maze, vertical grid hold …