Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis.
Hunter KE, Nguyen D, Libesman S, Williams JG, Aberoumand M, Aagerup J, Johnson BJ, Golley RK, Barba A, Sotiropoulos JX, Shrestha N, Palacios T, Pryde SJ, Wolfenden L, Taylor RW, Godolphin PJ, Matvienko-Sikar K, Sanders LM, Robledo KP, Brown V, Wood CT, Taki S, Yin HS, Hayes AJ, O'Connor DA, Smith W, Espinoza DE, Askie L, Chadwick PM, Rissel C, Webster AC, Hesketh KD, Bryant M, Thomson JL, Lakshman R, Fiks AG, Helle C, Odar Stough C, Ong KK, Perrin EM, Karssen L, Larsen JK, Linares AM, Messito MJ, Wen LM, Oken E, Øverby NC, Palacios C, Paul IM, Rasmussen FE, Reifsnider EA, Rothman RL, Byrne RA, Rybak TM, Salvy SJ, Wasser HM, Thompson AL, Ghaderi A, Taylor BJ, Maffeis C, Xu H, Savage JS, Joshipura KJ, de la Haye K, Røed M, Copsey B, Golova N, Gross RS, Anzman-Frasca S, Banna J, Baur LA, Seidler AL; TOPCHILD Collaboration.
Hunter KE, et al.
Lancet. 2025 Sep 20;406(10509):1235-1254. doi: 10.1016/S0140-6736(25)01144-4. Epub 2025 Sep 10.
Lancet. 2025.
PMID: 40945528
Free PMC article.
Of these, 18 (38%) assessed our primary outcome, BMI Z score. We obtained individual participant data for 17 (94%; n=9128) of these 18 trials (n=9383), representing 97% of eligible participants. ...We found no evidence of an effect of interventions on BMI Z score at …
Of these, 18 (38%) assessed our primary outcome, BMI Z score. We obtained individual participant data for 17 (94%; n=9128) of these 1 …