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1946 407
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1948 1300
1949 906
1950 2036
1951 2829
1952 3121
1953 3435
1954 3397
1955 3484
1956 2957
1957 3023
1958 3168
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1967 4556
1968 5032
1969 5198
1970 5248
1971 5660
1972 5987
1973 5514
1974 5151
1975 4642
1976 4673
1977 4412
1978 4208
1979 4439
1980 4136
1981 4122
1982 3778
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1984 3776
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1986 4161
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1988 4283
1989 4453
1990 4017
1991 3078
1992 2482
1993 2571
1994 2484
1995 2565
1996 2776
1997 2554
1998 2698
1999 2653
2000 2704
2001 2413
2002 2295
2003 2258
2004 2279
2005 2318
2006 2188
2007 2030
2008 2170
2009 2336
2010 2314
2011 2342
2012 2458
2013 2600
2014 2644
2015 2577
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2017 2267
2018 2003
2019 1978
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2025 1647

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245,644 results

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The following term was not found in PubMed: Pourzakariya
Page 1
ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition.
He J, Zhu Y, Tian Z, Liu M, Gao A, Fu W, Lu F, Sun Y, Guo Y, Pan R, Ji Y, Chen J, Lu H, Lin J, Liang X, Kim C, Zhou C, Jiao H. He J, et al. Mol Cell. 2025 May 1;85(9):1790-1805.e7. doi: 10.1016/j.molcel.2025.04.004. Epub 2025 Apr 22. Mol Cell. 2025. PMID: 40267921
Z-DNA-binding protein 1 (ZBP1; also known as DAI or DLM-1) regulates cell death and inflammation by sensing left-handed double-helical nucleic acids, including Z-RNA and Z-DNA. However, the physiological conditions that generate Z-form nucleic acids ( …
Z-DNA-binding protein 1 (ZBP1; also known as DAI or DLM-1) regulates cell death and inflammation by sensing left-handed double-helica …
Z-DNA and Z-RNA in human disease.
Herbert A. Herbert A. Commun Biol. 2019 Jan 7;2:7. doi: 10.1038/s42003-018-0237-x. eCollection 2019. Commun Biol. 2019. PMID: 30729177 Free PMC article. Review.
Left-handed Z-DNA/Z-RNA is bound with high affinity by the Zalpha domain protein family that includes ADAR (a double-stranded RNA editing enzyme), ZBP1 and viral orthologs regulating innate immunity. ...Loss of DICER1 function produces age-related macular degenerati …
Left-handed Z-DNA/Z-RNA is bound with high affinity by the Zalpha domain protein family that includes ADAR (a double-stranded …
Comparative review on left-handed Z-DNA.
Roy R, Chakraborty P, Chatterjee A, Sarkar J. Roy R, et al. Front Biosci (Landmark Ed). 2021 Apr 30;26(5):29-35. doi: 10.52586/4922. Front Biosci (Landmark Ed). 2021. PMID: 34027648 Free article. Review.
The high denseness of salt is required for conversion of B configuration d(CG)n toward Z configuration. The rate of B to Z transition is measured by "Cytosine Analogues" and "Fluorescence Spectroscopy". h-ZalphaADAR1 that a Z-DNA's binding domain, binds and s …
The high denseness of salt is required for conversion of B configuration d(CG)n toward Z configuration. The rate of B to Z tra …
Z-DNA crystallography .
Ho PS, Mooers BH. Ho PS, et al. Biopolymers. 1997;14(1):65-90. doi: 10.1002/(SICI)1097-0282(1997)44:1<65::AID-BIP5>3.0.CO;2-Y. Biopolymers. 1997. PMID: 19174848
These are discussed in terms of their effect on the ability of sequences to adopt the unusual Z-DNA structure. In addition, the experimental and theoretical methods used to treat DNA hydration are discussed as they relate to the stability of Z-DNA . Finally, we argu …
These are discussed in terms of their effect on the ability of sequences to adopt the unusual Z-DNA structure. In addition, the exper …
AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization.
Fang Y, Bansal K, Mostafavi S, Benoist C, Mathis D. Fang Y, et al. Nature. 2024 Apr;628(8007):400-407. doi: 10.1038/s41586-024-07169-7. Epub 2024 Mar 13. Nature. 2024. PMID: 38480882 Free PMC article.
Here we implemented two orthogonal approaches to investigate AIRE's cis-regulatory mechanisms: construction of a convolutional neural network and leveraging natural genetic variation through analysis of F1 hybrid mice(5). Both approaches nominated Z-DNA and NFE2-MAF as put …
Here we implemented two orthogonal approaches to investigate AIRE's cis-regulatory mechanisms: construction of a convolutional neural networ …
Special Issue: A, B and Z: The Structure, Function and Genetics of Z-DNA and Z-RNA.
Herbert A, Karapetyan S, Poptsova M, Vasquez KM, Vicens Q, Vögeli B. Herbert A, et al. Int J Mol Sci. 2021 Jul 19;22(14):7686. doi: 10.3390/ijms22147686. Int J Mol Sci. 2021. PMID: 34299306 Free PMC article.
It is now difficult to believe that a biological function for the left-handed Z-DNA and Z-RNA conformations was once controversial. The papers in this Special Issue, "Z-DNA and Z-RNA: from Physical Structure to Biological Function", are based on presen …
It is now difficult to believe that a biological function for the left-handed Z-DNA and Z-RNA conformations was once controver …
Z-DNA marks the spot for AIRE.
Goldfarb Y, Abramson J. Goldfarb Y, et al. Cell Res. 2024 Aug;34(8):537-538. doi: 10.1038/s41422-024-00964-x. Cell Res. 2024. PMID: 38684778 Free PMC article. No abstract available.
Z-DNA, an active element in the genome.
Wang G, Vasquez KM. Wang G, et al. Front Biosci. 2007 May 1;12:4424-38. doi: 10.2741/2399. Front Biosci. 2007. PMID: 17485386 Review.
Z-DNA is a left-handed helical form of DNA in which the double helix winds to the left in a zigzag pattern. ...In this review, we discuss the properties of Z-DNA, proteins that are known to bind specifically to Z-DNA, and potential biological functions of thi …
Z-DNA is a left-handed helical form of DNA in which the double helix winds to the left in a zigzag pattern. ...In this review, we dis …
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction.
Xie F, Wu D, Huang J, Liu X, Shen Y, Huang J, Su Z, Li J. Xie F, et al. Cell Death Dis. 2024 Jul 9;15(7):487. doi: 10.1038/s41419-024-06889-y. Cell Death Dis. 2024. PMID: 38982083 Free PMC article.
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zalphabeta domain, initiating downstream interactions with RIPK1 and RIPK3 via RHIM domains. ...How Zalphabeta and RHIM domain coop …
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) thr …
C8-Guanine modifications: effect on Z-DNA formation and its role in cancer.
Vongsutilers V, Gannett PM. Vongsutilers V, et al. Org Biomol Chem. 2018 Mar 28;16(13):2198-2209. doi: 10.1039/c8ob00030a. Org Biomol Chem. 2018. PMID: 29532848 Review.
In this comprehensive review, Z-DNA and the effect of prevalent C8-guanine adducts on the B-Z transition are addressed. The discoveries of Z-DNA binding proteins including ADAR1, E3L, DLM1, and PKZ have suggested the relevance of Z-DNA in living system …
In this comprehensive review, Z-DNA and the effect of prevalent C8-guanine adducts on the B-Z transition are addressed. The di …
245,644 results
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