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CXCL10: most consistent cGVHD biomarker?
Paczesny S, Abu Zaid M. Paczesny S, et al. Blood. 2016 Jun 16;127(24):2950-1. doi: 10.1182/blood-2016-04-709543. Blood. 2016. PMID: 27313326 Free PMC article.
In this issue of Blood, Kariminia et al report that serum CXCL10 is the only consistent biomarker for chronic graft-versus-host disease (cGVHD) and is associated with low peripheral blood levels of CXCR3(+) natural killer (NK) cells....
In this issue of Blood, Kariminia et al report that serum CXCL10 is the only consistent biomarker for chronic graft-versus-host disea …
Severe Recurrent Bacterial Pneumonia Among Children Living With HIV.
Boettiger DC, An VT, Lumbiganon P, Wittawatmongkol O, Huu Truong K, Chau Do V, Van Nguyen L, Sun Ly P, Kinikar A, Ounchanum P, Puthanakit T, Kurniati N, Kumarasamy N, Kumara Wati D, Chokephaibulkit K, Jamal Mohamed TA, Sudjaritruk T, Nik Yusoff NK, Siew Fong M, Nallusamy RA, Kariminia A; TREAT Asia Pediatric HIV Observational Database. Boettiger DC, et al. Pediatr Infect Dis J. 2022 May 1;41(5):e208-e215. doi: 10.1097/INF.0000000000003494. Pediatr Infect Dis J. 2022. PMID: 35185140 Free PMC article.

Clinical factors associated with severe recurrent bacterial pneumonia were younger age [adjusted subdistribution hazard ratio (aHR): 4.4 for <5 years versus 10 years, 95% CI: 2.2-8.4, P < 0.001], lower weight-for-age z-score (aHR: 1.5 for <-3.0 versus >-2.0, 95

Clinical factors associated with severe recurrent bacterial pneumonia were younger age [adjusted subdistribution hazard ratio (aHR): 4.4 for …
Antiretroviral Therapy in Severely Malnourished, HIV-infected Children in Asia.
Boettiger DC, Aurpibul L, Hudaya DM, Fong SM, Lumbiganon P, Saphonn V, Truong KH, Hansudewechakul R, Nguyen LV, Do VC, Bunupuradah T, Chokephaibulkit K, Nik Yusoff NK, Kumarasamy N, Wati DK, Razali KA, Kariminia A; TREAT Asia Pediatric HIV Observational Database. Boettiger DC, et al. Pediatr Infect Dis J. 2016 May;35(5):e144-51. doi: 10.1097/INF.0000000000001074. Pediatr Infect Dis J. 2016. PMID: 26835972 Free PMC article.
METHODS: Children enrolled in the TREAT Asia Pediatric HIV Observational Database who had SM (weight-for-height or body mass index-for-age Z score less than -3) at ART initiation were analyzed. Generalized estimating equations were used to investigate poor weight recovery …
METHODS: Children enrolled in the TREAT Asia Pediatric HIV Observational Database who had SM (weight-for-height or body mass index-for-age …
Outcomes of second-line antiretroviral therapy among children living with HIV: a global cohort analysis.
Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration. Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration. J Int AIDS Soc. 2020 Apr;23(4):e25477. doi: 10.1002/jia2.25477. J Int AIDS Soc. 2020. PMID: 32297485 Free PMC article.
Improvements in CD4 counts were observed over two years of follow-up, particularly in regions with lower CD4 counts at second-line switch. Improvements in weight-for-age z-scores were not observed during follow-up. Cumulative incidence of LTFU at two years was <5% in al …
Improvements in CD4 counts were observed over two years of follow-up, particularly in regions with lower CD4 counts at second-line switch. I …
Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis.
Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration; Jesson J, Crichton S, Quartagno M, Yotebieng M, Abrams EJ, Chokephaibulkit K, Le Coeur S, Aké-Assi MH, Patel K, Pinto J, Paul M, Vreeman R, Davies MA, Ben-Farhat J, Van Dyke R, Judd A, Mofenson L, Vicari M, Seage G 3rd, Bekker LG, Essajee S, Gibb D, Penazzato M, Collins IJ, Wools-Kaloustian K, Slogrove A, Powis K, Williams P, Matshaba M, Thahane L, Nyasulu P, Lukhele B, Mwita L, Kekitiinwa-Rukyalekere A, Wanless S, Goetghebuer T, Thorne C, Warszawski J, Galli L, van Rossum AMC, Giaquinto C, Marczynska M, Marques L, Prata F, Ene L, Okhonskaya L, Navarro M, Frick A, Naver L, Kahlert C, Volokha A, Chappell E, Pape JW, Rouzier V, Marcelin A, Succi R, Sohn AH, Kariminia A, Edmonds A, Lelo P, Lyamuya R, Ogalo EA, Odhiambo FA, Haas AD, Bolton C, Muhairwe J, Tweya H, Sylla M, D'Almeida M, Renner L, Abzug MJ, Oleske J, Purswani M, Teasdale C, Nuwagaba-Biribonwoha H, Goodall R, Leroy V. Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration, et al. J Int AIDS Soc. 2022 Mar;25(3):e25871. doi: 10.1002/jia2.25871. J Int AIDS Soc. 2022. PMID: 35255197 Free PMC article.
Growth was measured using height-for-age Z-scores (HAZ, stunting if <-2 SD, WHO growth charts). Linear mixed-effects models were used to study the evolution of each outcome between ages 10 and 17. ...
Growth was measured using height-for-age Z-scores (HAZ, stunting if <-2 SD, WHO growth charts). Linear mixed-effects models were u …
Early Height and Weight Changes in Children Using Cotrimoxazole Prophylaxis With Antiretroviral Therapy.
Boettiger DC, Muktiarti D, Kurniati N, Truong KH, Saghayam S, Ly PS, Hansudewechakul R, Van Nguyen L, Do VC, Sudjaritruk T, Lumbiganon P, Chokephaibulkit K, Bunupuradah T, Nik Yusoff NK, Wati DK, Mohd Razali KA, Fong MS, Nallusamy RA, Sohn AH, Kariminia A; Therapeutics Research, Education, and AIDS Training in Asia (TREAT Asia) Pediatric HIV Observational Database. Boettiger DC, et al. Clin Infect Dis. 2016 Nov 1;63(9):1236-1244. doi: 10.1093/cid/ciw514. Epub 2016 Jul 28. Clin Infect Dis. 2016. PMID: 27470239 Free PMC article.
Generalized estimating equations were used to identify factors associated with change in height-for-age z-score (HAZ), follow-up HAZ -2, change in weight-for-age z-score (WAZ), and follow-up WAZ -2. ...
Generalized estimating equations were used to identify factors associated with change in height-for-age z-score (HAZ), follow-up HAZ …
Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy in Perinatally HIV-Infected, Treatment-Naïve Adolescents in Asia.
Boettiger DC, Sudjaritruk T, Nallusamy R, Lumbiganon P, Rungmaitree S, Hansudewechakul R, Kumarasamy N, Bunupuradah T, Saphonn V, Truong KH, Yusoff NKN, Do VC, Nguyen LV, Razali KAM, Fong SM, Kurniati N, Kariminia A. Boettiger DC, et al. J Adolesc Health. 2016 Apr;58(4):451-459. doi: 10.1016/j.jadohealth.2015.11.006. Epub 2016 Jan 20. J Adolesc Health. 2016. PMID: 26803201 Free PMC article.
After 5 years of treatment, median height-for-age z score increased from -2.3 to -1.6, and median CD4+ cell count increased from 131 to 580 cells/mm(3). ...
After 5 years of treatment, median height-for-age z score increased from -2.3 to -1.6, and median CD4+ cell count increased from 131 …
Survival of HIV-infected children: a cohort study from the Asia-Pacific region.
Lumbiganon P, Kariminia A, Aurpibul L, Hansudewechakul R, Puthanakit T, Kurniati N, Kumarasamy N, Chokephaibulkit K, Nik Yusoff NK, Vonthanak S, Moy FS, Razali KA, Nallusamy R, Sohn AH; TREAT Asia Pediatric HIV Observational Database (TApHOD). Lumbiganon P, et al. J Acquir Immune Defic Syndr. 2011 Apr;56(4):365-71. doi: 10.1097/QAI.0b013e318207a55b. J Acquir Immune Defic Syndr. 2011. PMID: 21160429 Free PMC article.
Those with a low recent CD4 percentage, who started ART with lower baseline weight-for-age Z score, or with WHO clinical stage 4 had an increased risk of death. Of 528 (23%) children who never received ART, 36 (6.8%) died after presenting to care, giving a crude mortality …
Those with a low recent CD4 percentage, who started ART with lower baseline weight-for-age Z score, or with WHO clinical stage 4 had …
Weight as predictors of clinical progression and treatment failure: results from the TREAT Asia Pediatric HIV Observational Database.
Kariminia A, Durier N, Jourdain G, Saghayam S, Do CV, Nguyen LV, Hansudewechakul R, Lumbiganon P, Chokephaibulkit K, Truong KH, Sirisanthana V, Ung V, Vonthanak S, Ananworanich J, Nik Yusoff NK, Kurniati N, Azahar Razali K, Fong MS, Nallusamy R, Wati DK; TREAT Asia Pediatric HIV Observational Database. Kariminia A, et al. J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):71-6. doi: 10.1097/QAI.0000000000000227. J Acquir Immune Defic Syndr. 2014. PMID: 24872132 Free PMC article.

RESULTS: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score < -3 was associated with mortality (P < 0.001) independent of CD4% and < -2 was associated with immunological failure (P 0.03) independent of age

RESULTS: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score < -3 was as

26 results