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Page 1
Odronextamab monotherapy in R/R DLBCL after progression with CAR T-cell therapy: primary analysis of the ELM-1 study.
Topp MS, Matasar M, Allan JN, Ansell SM, Barnes JA, Arnason JE, Michot JM, Goldschmidt N, O'Brien SM, Abadi U, Avivi I, Cheng Y, Flink DM, Zhu M, Brouwer-Visser J, Chaudhry A, Mohamed H, Ambati S, Crombie JL. Topp MS, et al. Blood. 2025 Apr 3;145(14):1498-1509. doi: 10.1182/blood.2024027044. Blood. 2025. PMID: 39786390 Free PMC article. Clinical Trial.
Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet Diabetes Endocrinol. 2023 Dec;11(12):905-914. doi: 10.1016/S2213-8587(23)00253-X. Epub 2023 Oct 18. Lancet Diabetes Endocrinol. 2023. PMID: 37865101 Free PMC article. Clinical Trial.
FUNDING: UK Research and Innovation (Medical Research Council) and National Institute of Health Research (MC_PC_19056), and Wellcome Trust (222406/Z/20/Z). TRANSLATIONS: For the Nepali, Hindi, Indonesian (Bahasa) and Vietnamese translations of the abstract see Suppl …
FUNDING: UK Research and Innovation (Medical Research Council) and National Institute of Health Research (MC_PC_19056), and Wellcome Trust ( …
The OHI index predicts early mortality from organ dysfunction and survival benefit from etoposide in patients with lymphoma.
Zoref-Lorenz A, Murakami J, Gurion R, Iyer SP, Abadi U, Cohen I, Goyal G, Mohamed S, Nikiforow S, Natour AEH, Weinstein S, Yacobovich J, Cho HL, Raanani P, Nagler A, Berliner N, Daver N, Itchaki G, Izraeli S, Ellis M, Jordan MB. Zoref-Lorenz A, et al. Blood Adv. 2025 Sep 9;9(17):4515-4525. doi: 10.1182/bloodadvances.2024014005. Blood Adv. 2025. PMID: 40249910 Free PMC article.
Design, synthesis, and metabolite identification of Tamoxifen esterase-activatable prodrugs.
Elbagoury RM, Shenouda MA, Elnakib HE, Wober J, Abadi AH, Ahmed NS. Elbagoury RM, et al. Bioorg Chem. 2023 Feb;131:106303. doi: 10.1016/j.bioorg.2022.106303. Epub 2022 Nov 28. Bioorg Chem. 2023. PMID: 36455483
Hydrolysis of the carbamate moiety on ring C is mediated via carboxylesterases. Compound 3d [E/Z Benzyl-carbamic acid4-{2-benzyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-but-1-enyl}-phenyl ester] showed GI(50) = 0.09 M on MCF-7 and GI(50) = 1.84 M on MDA-MB231 cell lines. . …
Hydrolysis of the carbamate moiety on ring C is mediated via carboxylesterases. Compound 3d [E/Z Benzyl-carbamic acid4-{2-benzyl-1-[4 …
Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability.
Harms M, Fabech Hansson R, Gilg A, Almeida-Hernández Y, Löffler J, Rodríguez-Alfonso A, Habib MMW, Albers D, Ahmed NS, Abadi AH, Winter G, Rasche V, Beer AJ, Weidinger G, Preising N, Ständker L, Wiese S, Sanchez-Garcia E, Zelikin AN, Münch J. Harms M, et al. J Med Chem. 2023 Nov 23;66(22):15189-15204. doi: 10.1021/acs.jmedchem.3c01128. Epub 2023 Nov 8. J Med Chem. 2023. PMID: 37940118 Free PMC article.
A systematic review and meta-analysis on the treatment of liver hydatid cyst: Comparing laparoscopic and open surgeries.
Sokouti M, Sadeghi R, Pashazadeh S, Abadi SEH, Sokouti M, Rezaei-Hachesu P, Ghojazadeh M, Sokouti B. Sokouti M, et al. Arab J Gastroenterol. 2017 Sep;18(3):127-135. doi: 10.1016/j.ajg.2017.09.010. Epub 2017 Oct 4. Arab J Gastroenterol. 2017. PMID: 28988788
In this meta-analysis study, random effects models of outcomes (i.e. post-operative complications, mortalities, recurrences and cure rate) of the two procedures were OR=0.852, LL=0.469, UL=1.546, Z=-0.526, p=0.599 (for post-operative complications); OR=0.849, LL=0.141, UL= …
In this meta-analysis study, random effects models of outcomes (i.e. post-operative complications, mortalities, recurrences and cure rate) o …
Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. EClinicalMedicine. 2025 Feb 12;81:103080. doi: 10.1016/j.eclinm.2025.103080. eCollection 2025 Mar. EClinicalMedicine. 2025. PMID: 40036152 Free PMC article.
FUNDING: UK Research and Innovation (Medical Research Council) and National Institute for Health Research (Grant ref: MC_PC_19056), and Wellcome Trust (Grant Ref: 222406/Z/20/Z)....
FUNDING: UK Research and Innovation (Medical Research Council) and National Institute for Health Research (Grant ref: MC_PC_19056), and Well …
Flexible Etherified and Esterified Triphenylethylene Derivatives and Their Evaluation on ER-positive and Triple-Negative Breast Cancer Cell Lines.
Hassan AS, Wober J, Vollmer G, Abadi AH, Ahmed NS. Hassan AS, et al. ChemMedChem. 2022 Apr 5;17(7):e202100720. doi: 10.1002/cmdc.202100720. Epub 2022 Feb 17. ChemMedChem. 2022. PMID: 35076180
Compounds have either an ester group on ring C or homodiaminoalkoxy groups on rings B and C. Compound 6 (E/Z-4-[1-[4-(2-diethylaminoethoxy)phenyl]-3-(4-methoxyphenyl)-2-methyl[propenyl]phenol) was found to be ten-fold more potent than TAM on MCF-7 cells (GI(50) =0.15 muM). …
Compounds have either an ester group on ring C or homodiaminoalkoxy groups on rings B and C. Compound 6 (E/Z-4-[1-[4-(2-diethylaminoe …
Electronic Structure of the Alternating Monolayer-Trilayer Phase of La_{3}Ni_{2}O_{7}.
Abadi S, Xu KJ, Lomeli EG, Puphal P, Isobe M, Zhong Y, Fedorov AV, Mo SK, Hashimoto M, Lu DH, Moritz B, Keimer B, Devereaux TP, Hepting M, Shen ZX. Abadi S, et al. Phys Rev Lett. 2025 Mar 28;134(12):126001. doi: 10.1103/PhysRevLett.134.126001. Phys Rev Lett. 2025. PMID: 40215506 Free article.
By comparison to local-density approximation calculations, we find renormalizations of the Ni-d_{z^{2}} and Ni-d_{x^{2}-y^{2}} derived bands to be about 5 to 7 and about 4, respectively, suggesting strong correlation effects. ...
By comparison to local-density approximation calculations, we find renormalizations of the Ni-d_{z^{2}} and Ni-d_{x^{2}-y^{2}} derive …
Deep silicon photon-counting CT: A first simulation-based study for assessing perceptual benefits across diverse anatomies.
Sharma S, Pal D, Abadi E, Segars P, Hsieh J, Samei E. Sharma S, et al. Eur J Radiol. 2024 Feb;171:111279. doi: 10.1016/j.ejrad.2023.111279. Epub 2023 Dec 26. Eur J Radiol. 2024. PMID: 38194843 Free PMC article.
The reconstructed pairs of images were scored by radiologists to gauge the task-specific perceptual benefits provided by Si-PCCT compared to ECT based on visualization of anatomical and image quality features. The scores were standardized as z-scores for minimizing inter-o …
The reconstructed pairs of images were scored by radiologists to gauge the task-specific perceptual benefits provided by Si-PCCT compared to …
20 results