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Zinc finger protein 251 deficiency impairs glucose metabolism by inducing adipocyte hypertrophy.
Kim E, Ham SA, Hwang JS, Won JP, Lee HG, Hur J, Seo HG. Kim E, et al. Mol Cell Endocrinol. 2023 Feb 15;562:111838. doi: 10.1016/j.mce.2022.111838. Epub 2022 Dec 21. Mol Cell Endocrinol. 2023. PMID: 36565788
Gene ontology analysis revealed that ZFP251 deficiency affected the expression of genes associated with adipocyte differentiation and lipid and fatty acid metabolism. ...These results suggest that ZFP251 deficiency causes impaired adipogenesis and adipocyte hypertro …
Gene ontology analysis revealed that ZFP251 deficiency affected the expression of genes associated with adipocyte differentiation and …
Functional screen identifies regulators of murine hematopoietic stem cell repopulation.
Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J, Saulsberry AC, Cico A, Gaut L, McGoldrick D, Finkelstein D, Tan K, McKinney-Freeman S. Holmfeldt P, et al. J Exp Med. 2016 Mar 7;213(3):433-49. doi: 10.1084/jem.20150806. Epub 2016 Feb 15. J Exp Med. 2016. PMID: 26880577 Free PMC article.
We identified 17 regulators of HSPC repopulation: Arhgef5, Armcx1, Cadps2, Crispld1, Emcn, Foxa3, Fstl1, Glis2, Gprasp2, Gpr56, Myct1, Nbea, P2ry14, Smarca2, Sox4, Stat4, and Zfp251. Knockdown of each of these genes yielded a loss of function, except in the cases of Armcx1 …
We identified 17 regulators of HSPC repopulation: Arhgef5, Armcx1, Cadps2, Crispld1, Emcn, Foxa3, Fstl1, Glis2, Gprasp2, Gpr56, Myct1, Nbea, …