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Page 1
Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73.
Shi C, Chang L, Wang J, Dai J, Xu W, Tang J, Mei W, Zhang C, Wang Z, Liao Y, Zhang X, Jiang W, Zhang G, Zhao Z, Xu Y, Zhu L, Li H. Shi C, et al. Among authors: zhao z. J Med Chem. 2024 Jun 13;67(11):9686-9708. doi: 10.1021/acs.jmedchem.4c00825. Epub 2024 May 29. J Med Chem. 2024. PMID: 38809692
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Among authors: zhao z. Protein Cell. 2020 Oct;11(10):723-739. doi: 10.1007/s13238-020-00768-w. Epub 2020 Aug 4. Protein Cell. 2020. PMID: 32754890 Free PMC article.
Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2.
Li W, Mei W, Jiang H, Wang J, Li X, Quan L, Diao Y, Ma Y, Fan S, Xie Z, Gong M, Zhu H, Bi D, Zhang F, Ma L, Zhang J, Gao Y, Paschalidis A, Lin H, Liu F, Liu K, Ye M, Zhao Z, Duan Y, Chen Z, Xu Y, Xiao W, Tao S, Zhu L, Li H. Li W, et al. Among authors: zhao z. Sci China Life Sci. 2025 Jan;68(1):189-203. doi: 10.1007/s11427-024-2706-2. Epub 2024 Aug 29. Sci China Life Sci. 2025. PMID: 39235560
90 results