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Year Number of Results
2007 1
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2013 1
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13 results

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Page 1
Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists.
Chen M, Guo Z, Lanier MC, Zhao L, Betz SF, Huang CQ, Loweth CJ, Ashweek NJ, Liu XJ, Struthers RS, Bradbury MJ, Behan JW, Wen J, O'Brien Z, Saunders J, Zhu YF. Chen M, et al. Among authors: o brien z. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3845-50. doi: 10.1016/j.bmcl.2007.05.009. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17521908
Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia.
Moree WJ, Li BF, Jovic F, Coon T, Yu J, Gross RS, Tucci F, Marinkovic D, Zamani-Kord S, Malany S, Bradbury MJ, Hernandez LM, O'Brien Z, Wen J, Wang H, Hoare SR, Petroski RE, Sacaan A, Madan A, Crowe PD, Beaton G. Moree WJ, et al. Among authors: o brien z. J Med Chem. 2009 Sep 10;52(17):5307-10. doi: 10.1021/jm900933k. J Med Chem. 2009. PMID: 19663387
N-[6-amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A2A receptor antagonists with improved drug like properties and in vivo efficacy.
Lanier MC, Moorjani M, Luo Z, Chen Y, Lin E, Tellew JE, Zhang X, Williams JP, Gross RS, Lechner SM, Markison S, Joswig T, Kargo W, Piercey J, Santos M, Malany S, Zhao M, Petroski R, Crespo MI, Díaz JL, Saunders J, Wen J, O'Brien Z, Jalali K, Madan A, Slee DH. Lanier MC, et al. Among authors: o brien z. J Med Chem. 2009 Feb 12;52(3):709-17. doi: 10.1021/jm800908d. J Med Chem. 2009. PMID: 19140664
Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease.
Zhang X, Tellew JE, Luo Z, Moorjani M, Lin E, Lanier MC, Chen Y, Williams JP, Saunders J, Lechner SM, Markison S, Joswig T, Petroski R, Piercey J, Kargo W, Malany S, Santos M, Gross RS, Wen J, Jalali K, O'Brien Z, Stotz CE, Crespo MI, Díaz JL, Slee DH. Zhang X, et al. Among authors: o brien z. J Med Chem. 2008 Nov 27;51(22):7099-110. doi: 10.1021/jm800851u. J Med Chem. 2008. PMID: 18947224
Novel benzothiophene H1-antihistamines for the treatment of insomnia.
Moree WJ, Jovic F, Coon T, Yu J, Li BF, Tucci FC, Marinkovic D, Gross RS, Malany S, Bradbury MJ, Hernandez LM, O'Brien Z, Wen J, Wang H, Hoare SR, Petroski RE, Sacaan A, Madan A, Crowe PD, Beaton G. Moree WJ, et al. Among authors: o brien z. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2316-20. doi: 10.1016/j.bmcl.2010.01.134. Epub 2010 Feb 2. Bioorg Med Chem Lett. 2010. PMID: 20188547
Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.
Slee DH, Zhang X, Moorjani M, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Wen J, O'Brien Z, Saunders J. Slee DH, et al. Among authors: o brien z. J Med Chem. 2008 Feb 14;51(3):400-6. doi: 10.1021/jm070623o. Epub 2008 Jan 12. J Med Chem. 2008. PMID: 18189346
13 results