Hybrid assembly with long and short reads improves discovery of gene family expansions.
Miller JR, Zhou P, Mudge J, Gurtowski J, Lee H, Ramaraj T, Walenz BP, Liu J, Stupar RM, Denny R, Song L, Singh N, Maron LG, McCouch SR, McCombie WR, Schatz MC, Tiffin P, Young ND, Silverstein KAT.
Miller JR, et al.
BMC Genomics. 2017 Jul 19;18(1):541. doi: 10.1186/s12864-017-3927-8.
BMC Genomics. 2017.
PMID: 28724409
Free PMC article.
METHODS: We developed a hybrid assembly pipeline called "Alpaca" that can operate on 20X long-read coverage plus about 50X short-insert and 50X long-insert short-read coverage. ...
METHODS: We developed a hybrid assembly pipeline called "Alpaca" that can operate on 20X long-read coverage plus about 50X short-inse …