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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
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1995 6
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1997 3
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1999 8
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2001 14
2002 18
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6,065 results

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The following term was not found in PubMed: sonisamide
Page 1
Efficacy and safety of semaglutide 2.4 mg for weight loss in overweight or obese adults without diabetes: An updated systematic review and meta-analysis including the 2-year STEP 5 trial.
Qin W, Yang J, Deng C, Ruan Q, Duan K. Qin W, et al. Diabetes Obes Metab. 2024 Mar;26(3):911-923. doi: 10.1111/dom.15386. Epub 2023 Nov 28. Diabetes Obes Metab. 2024. PMID: 38016699
Our aim was to identify randomized controlled trials (RCTs) that compared the efficacy of semaglutide administered once weekly with placebo in overweight or obese adults. Through a review of the literature, data were extracted from relevant studies and assessed for quality …
Our aim was to identify randomized controlled trials (RCTs) that compared the efficacy of semaglutide administered once weekly with placebo …
Fecal microbiota transplantation in obesity metabolism: A meta analysis and systematic review.
Zecheng L, Donghai L, Runchuan G, Yuan Q, Qi J, Yijia Z, Shuaman R, Xiaoqi L, Yi W, Ni M, Yijin Q, Liang P, Jun W. Zecheng L, et al. Diabetes Res Clin Pract. 2023 Aug;202:110803. doi: 10.1016/j.diabres.2023.110803. Epub 2023 Jun 24. Diabetes Res Clin Pract. 2023. PMID: 37356723 Free article.
OBJECTIVE: The effect of fecal microbiota transplantation (FMT) on microbiota engraftment in patients with metabolic syndrome remains unclear. This systematic review employed a meta-analysis of RCTs for assessment on the role of FMT in treating obesity and me …
OBJECTIVE: The effect of fecal microbiota transplantation (FMT) on microbiota engraftment in patients with metabolic syndrome remains unclea …
Is Fasting Superior to Continuous Caloric Restriction for Weight Loss and Metabolic Outcomes in Obese Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Siles-Guerrero V, Romero-Márquez JM, García-Pérez RN, Novo-Rodríguez C, Guardia-Baena JM, Hayón-Ponce M, Tenorio-Jiménez C, López-de-la-Torre-Casares M, Muñoz-Garach A. Siles-Guerrero V, et al. Nutrients. 2024 Oct 18;16(20):3533. doi: 10.3390/nu16203533. Nutrients. 2024. PMID: 39458528 Free PMC article.
Both aim to create a calorie deficit, but it is still uncertain as to which is more effective for short- and long-term weight and metabolic outcomes. OBJECTIVES: this systematic review and meta-analysis aimed to compare the effectiveness of FBS and CCR on these para …
Both aim to create a calorie deficit, but it is still uncertain as to which is more effective for short- and long-term weight and metabolic …
The Effect of the L-Carnitine Supplementation on Obesity Indices: An Umbrella Meta-Analysis.
Hamedi-Kalajahi F, Zarezadeh M, Malekahmadi M, Jamilian P, Jamilian P, Molani-Gol R, Ostadrahimi A. Hamedi-Kalajahi F, et al. Int J Vitam Nutr Res. 2025 Apr 28;95(2):40033. doi: 10.31083/IJVNR40033. Int J Vitam Nutr Res. 2025. PMID: 40298161 Free article.
However, given the inconclusive results from recent meta-analyses on L-carnitine, we conducted an umbrella meta-analysis of placebo-controlled and controlled trials to evaluate the effect of L-carnitine on anthropometric indices. ...CONCLUSION: The findings of this …
However, given the inconclusive results from recent meta-analyses on L-carnitine, we conducted an umbrella meta-analysis of pl …
Long-Term Weight Loss Strategies for Obesity.
Kheniser K, Saxon DR, Kashyap SR. Kheniser K, et al. J Clin Endocrinol Metab. 2021 Jun 16;106(7):1854-1866. doi: 10.1210/clinem/dgab091. J Clin Endocrinol Metab. 2021. PMID: 33595666 Free PMC article. Review.
CONTEXT: Obesity is a chronic disease that is difficult to manage without holistic therapy. The therapeutic armamentarium for obesity primarily consists of 4 forms of therapy: lifestyle modification (ie, diet and exercise), cognitive behavioral ther …
CONTEXT: Obesity is a chronic disease that is difficult to manage without holistic therapy. The therapeutic armamentarium for …
Gastrointestinal adverse events associated with GLP-1 RA in non-diabetic patients with overweight or obesity: a systematic review and network meta-analysis.
Ismaiel A, Scarlata GGM, Boitos I, Leucuta DC, Popa SL, Al Srouji N, Abenavoli L, Dumitrascu DL. Ismaiel A, et al. Int J Obes (Lond). 2025 Oct;49(10):1946-1957. doi: 10.1038/s41366-025-01859-6. Epub 2025 Aug 13. Int J Obes (Lond). 2025. PMID: 40804463 Free PMC article.
Research often focuses on diabetics, leaving a gap in understanding their effects on non-diabetic individuals with overweight or obesity. This systematic review and dose-response network meta-analysis addresses this gap, analyzing gastrointestinal adverse eve …
Research often focuses on diabetics, leaving a gap in understanding their effects on non-diabetic individuals with overweight or obesity …
Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials.
Patikorn C, Roubal K, Veettil SK, Chandran V, Pham T, Lee YY, Giovannucci EL, Varady KA, Chaiyakunapruk N. Patikorn C, et al. JAMA Netw Open. 2021 Dec 1;4(12):e2139558. doi: 10.1001/jamanetworkopen.2021.39558. JAMA Netw Open. 2021. PMID: 34919135 Free PMC article.
OBJECTIVE: To grade the evidence from published meta-analyses of RCTs that assessed the associations of IF (zero-calorie alternate-day fasting, modified alternate-day fasting, the 5:2 diet, and time-restricted eating) with obesity-related health outcomes. EVIDENCE REVIEW: …
OBJECTIVE: To grade the evidence from published meta-analyses of RCTs that assessed the associations of IF (zero-calorie alternate-day fasti …
Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials.
Franz MJ, Boucher JL, Rutten-Ramos S, VanWormer JJ. Franz MJ, et al. J Acad Nutr Diet. 2015 Sep;115(9):1447-63. doi: 10.1016/j.jand.2015.02.031. Epub 2015 Apr 29. J Acad Nutr Diet. 2015. PMID: 25935570
The majority of people with type 2 diabetes are overweight or obese, and weight loss is a recommended treatment strategy. A systematic review and meta-analysis was undertaken to answer the following primary question: In overweight or obese adult …
The majority of people with type 2 diabetes are overweight or obese, and weight loss is a recommended treatment strategy. A sy …
Bariatric surgery: a systematic review and meta-analysis.
Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, Schoelles K. Buchwald H, et al. JAMA. 2004 Oct 13;292(14):1724-37. doi: 10.1001/jama.292.14.1724. JAMA. 2004. PMID: 15479938
CONTEXT: About 5% of the US population is morbidly obese. This disease remains largely refractory to diet and drug therapy, but generally responds well to bariatric surgery. ...DATA SYNTHESIS: A random effects model was used in the meta-analysis. The m …
CONTEXT: About 5% of the US population is morbidly obese. This disease remains largely refractory to diet and drug therapy, bu …
Comparison of weight loss interventions in overweight and obese adults with knee osteoarthritis: A systematic review and network meta-analysis of randomized trials.
Shahid A, Thirumaran AJ, Christensen R, Venkatesha V, Henriksen M, Bowden JL, Hunter DJ. Shahid A, et al. Osteoarthritis Cartilage. 2025 Apr;33(4):518-529. doi: 10.1016/j.joca.2024.08.012. Epub 2024 Sep 2. Osteoarthritis Cartilage. 2025. PMID: 39233046 Free article.
OBJECTIVE: To ascertain the comparative effectiveness of weight-loss strategies for osteoarthritis (OA) to develop rational treatment algorithms aimed at improving OA-related symptoms in overweight/obese individuals. ...CONCLUSIONS: PDE and DE interventions may offe …
OBJECTIVE: To ascertain the comparative effectiveness of weight-loss strategies for osteoarthritis (OA) to develop rational treatment …
6,065 results