An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.
Corces MR, Trevino AE, Hamilton EG, Greenside PG, Sinnott-Armstrong NA, Vesuna S, Satpathy AT, Rubin AJ, Montine KS, Wu B, Kathiria A, Cho SW, Mumbach MR, Carter AC, Kasowski M, Orloff LA, Risca VI, Kundaje A, Khavari PA, Montine TJ, Greenleaf WJ, Chang HY.
Corces MR, et al.
Nat Methods. 2017 Oct;14(10):959-962. doi: 10.1038/nmeth.4396. Epub 2017 Aug 28.
Nat Methods. 2017.
PMID: 28846090
Free PMC article.
The Omni-ATAC protocol generates chromatin accessibility profiles from archival frozen tissue samples and 50-mum sections, revealing the activities of disease-associated DNA elements in distinct human brain structures. ...
The Omni-ATAC protocol generates chromatin accessibility profiles from archival frozen tissue samples and 50-mum sections, revealing …