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Design and synthesis of 4,5-diphenyl-imidazol-1,2,3-triazole hybrids as new anti-diabetic agents: in vitro α-glucosidase inhibition, kinetic and docking studies.
Asgari MS, Mohammadi-Khanaposhtani M, Sharafi Z, Faramarzi MA, Rastegar H, Nasli Esfahani E, Bandarian F, Ranjbar Rashidi P, Rahimi R, Biglar M, Mahdavi M, Larijani B. Asgari MS, et al. Mol Divers. 2021 May;25(2):877-888. doi: 10.1007/s11030-020-10072-8. Epub 2020 Mar 18. Mol Divers. 2021. PMID: 32189236
Fourteen novel 4,5-diphenyl-imidazol-1,2,3-triazole hybrids 8a-n were synthesized with good yields by performing click reaction between the 4,5-diphenyl-2-(prop-2-yn-1-ylthio)-1H-imidazole and various benzyl azides. The synthesized compounds 8a-n were evaluated against yea …
Fourteen novel 4,5-diphenyl-imidazol-1,2,3-triazole hybrids 8a-n were synthesized with good yields by performing click reaction between the …
Highly Active and Reusable Cu/C Catalyst for Synthesis of 5-Substituted 1H-Tetrazoles Starting from Aromatic Aldehydes.
Khalifeh R, Rastegar N, Khalili D. Khalifeh R, et al. Acta Chim Slov. 2020 Dec;67(4):1044-1052. Acta Chim Slov. 2020. PMID: 33533457
The synthesis was performed by the one-pot three-component [3+2]cycloaddition reaction between aldehyde, hydroxylamine and sodium azide in the presence of Cu/C. The reaction probably proceeds by the in situ formation of nitriles followed by successive [3+2]cycloaddition wi …
The synthesis was performed by the one-pot three-component [3+2]cycloaddition reaction between aldehyde, hydroxylamine and sodium azide …