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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1974 1
1977 1
1978 2
1979 1
1981 1
1982 3
1983 1
1984 2
1992 1
2004 1
2005 2
2006 1
2007 4
2008 1
2009 1
2011 1
2012 5
2013 3
2014 6
2015 5
2016 8
2017 4
2018 1
2019 4
2020 3
2021 1
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59 results
Results by year
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Page 1
Discovery of quinoline-based irreversible BTK inhibitors.
de Bruin G, Demont D, de Zwart E, Verkaik S, Hoogenboom N, van de Kar B, van Lith B, Emmelot-van Hoek M, Gulrajani M, Covey T, Kaptein A, Barf T. de Bruin G, et al. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127261. doi: 10.1016/j.bmcl.2020.127261. Epub 2020 May 13. Bioorg Med Chem Lett. 2020. PMID: 32527559
Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits.
Xin BT, Huber EM, de Bruin G, Heinemeyer W, Maurits E, Espinal C, Du Y, Janssens M, Weyburne ES, Kisselev AF, Florea BI, Driessen C, van der Marel GA, Groll M, Overkleeft HS. Xin BT, et al. Among authors: de bruin g. J Med Chem. 2019 Feb 14;62(3):1626-1642. doi: 10.1021/acs.jmedchem.8b01884. Epub 2019 Feb 5. J Med Chem. 2019. PMID: 30657666 Free PMC article.
Sleep Pathology in Creutzfeldt-Jakob Disease.
Kang P, de Bruin GS, Wang LH, Ward BA, Ances BM, Lim MM, Bucelli RC. Kang P, et al. Among authors: de bruin gs. J Clin Sleep Med. 2016 Jul 15;12(7):1033-9. doi: 10.5664/jcsm.5944. J Clin Sleep Med. 2016. PMID: 27250807 Free PMC article.
Proteasome inhibitors with photocontrolled activity.
Hansen MJ, Velema WA, de Bruin G, Overkleeft HS, Szymanski W, Feringa BL. Hansen MJ, et al. Among authors: de bruin g. Chembiochem. 2014 Sep 22;15(14):2053-7. doi: 10.1002/cbic.201402237. Epub 2014 Aug 14. Chembiochem. 2014. PMID: 25125335
Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.
Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR 3rd, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT. Widjaja CE, et al. Among authors: de bruin g. J Clin Invest. 2017 Oct 2;127(10):3609-3623. doi: 10.1172/JCI90895. Epub 2017 Aug 28. J Clin Invest. 2017. PMID: 28846070 Free PMC article.
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