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Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant.
Zuo F, Abolhassani H, Du L, Piralla A, Bertoglio F, de Campos-Mata L, Wan H, Schubert M, Cassaniti I, Wang Y, Sammartino JC, Sun R, Vlachiotis S, Bergami F, Kumagai-Braesch M, Andréll J, Zhang Z, Xue Y, Wenzel EV, Calzolai L, Varani L, Rezaei N, Chavoshzadeh Z, Baldanti F, Hust M, Hammarström L, Marcotte H, Pan-Hammarström Q. Zuo F, et al. Among authors: de campos mata l. Nat Commun. 2022 May 13;13(1):2670. doi: 10.1038/s41467-022-30340-5. Nat Commun. 2022. PMID: 35562366 Free PMC article.
The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.
Blasco-Moreno B, de Campos-Mata L, Böttcher R, García-Martínez J, Jungfleisch J, Nedialkova DD, Chattopadhyay S, Gas ME, Oliva B, Pérez-Ortín JE, Leidel SA, Choder M, Díez J. Blasco-Moreno B, et al. Among authors: de campos mata l. Nat Commun. 2019 Mar 21;10(1):1298. doi: 10.1038/s41467-019-09199-6. Nat Commun. 2019. PMID: 30899024 Free PMC article.
SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses.
de Campos-Mata L, Tejedor Vaquero S, Tachó-Piñot R, Piñero J, Grasset EK, Arrieta Aldea I, Rodrigo Melero N, Carolis C, Horcajada JP, Cerutti A, Villar-García J, Magri G. de Campos-Mata L, et al. Clin Transl Immunology. 2021 Sep 5;10(9):e1339. doi: 10.1002/cti2.1339. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34504693 Free PMC article.
The mRNA-1273 Vaccine Induces Cross-Variant Antibody Responses to SARS-CoV-2 With Distinct Profiles in Individuals With or Without Pre-Existing Immunity.
Tejedor Vaquero S, de Campos-Mata L, Ramada JM, Díaz P, Navarro-Barriuso J, Ribas-Llaurado C, Rodrigo Melero N, Carolis C, Cerutti A, Gimeno R, Magri G. Tejedor Vaquero S, et al. Among authors: de campos mata l. Front Immunol. 2021 Sep 3;12:737083. doi: 10.3389/fimmu.2021.737083. eCollection 2021. Front Immunol. 2021. PMID: 34539673 Free PMC article.