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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2000 1
2001 2
2003 1
2004 2
2005 8
2006 8
2007 7
2008 9
2009 9
2010 12
2011 18
2012 19
2013 12
2014 5
2015 8
2016 6
2017 2
2018 9
2019 14
2020 7
2021 9
2022 6
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158 results
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Page 1
Fragment-to-Lead Medicinal Chemistry Publications in 2017.
Mortenson PN, Erlanson DA, de Esch IJP, Jahnke W, Johnson CN. Mortenson PN, et al. Among authors: de esch ijp. J Med Chem. 2019 Apr 25;62(8):3857-3872. doi: 10.1021/acs.jmedchem.8b01472. Epub 2018 Nov 21. J Med Chem. 2019. PMID: 30462504 Review.
Structural Analysis of Chemokine Receptor-Ligand Interactions.
Arimont M, Sun SL, Leurs R, Smit M, de Esch IJP, de Graaf C. Arimont M, et al. Among authors: de esch ijp. J Med Chem. 2017 Jun 22;60(12):4735-4779. doi: 10.1021/acs.jmedchem.6b01309. Epub 2017 Mar 10. J Med Chem. 2017. PMID: 28165741 Free PMC article. Review.
Career development in fragment-based drug discovery.
Romasanta AKS, van der Sijde PC, Smit MJ, de Esch IJP, Jahnke W, van Muijlwijk-Koezen JE. Romasanta AKS, et al. Among authors: de esch ijp. Drug Discov Today Technol. 2020 Dec;37:107-116. doi: 10.1016/j.ddtec.2020.10.001. Epub 2020 Dec 1. Drug Discov Today Technol. 2020. PMID: 34895649 Free article. Review.
Progress in Free Energy Perturbation: Options for Evolving Fragments.
Zara L, Efrém NL, van Muijlwijk-Koezen JE, de Esch IJP, Zarzycka B. Zara L, et al. Among authors: de esch ijp. Drug Discov Today Technol. 2021 Dec;40:36-42. doi: 10.1016/j.ddtec.2021.10.001. Epub 2021 Nov 18. Drug Discov Today Technol. 2021. PMID: 34916020 Review.
The Landscape of Atypical and Eukaryotic Protein Kinases.
Kanev GK, de Graaf C, de Esch IJP, Leurs R, Würdinger T, Westerman BA, Kooistra AJ. Kanev GK, et al. Among authors: de esch ijp. Trends Pharmacol Sci. 2019 Nov;40(11):818-832. doi: 10.1016/j.tips.2019.09.002. Epub 2019 Oct 31. Trends Pharmacol Sci. 2019. PMID: 31677919 Free article. Review.
Fragment-to-Lead Medicinal Chemistry Publications in 2019.
Jahnke W, Erlanson DA, de Esch IJP, Johnson CN, Mortenson PN, Ochi Y, Urushima T. Jahnke W, et al. Among authors: de esch ijp. J Med Chem. 2020 Dec 24;63(24):15494-15507. doi: 10.1021/acs.jmedchem.0c01608. Epub 2020 Nov 23. J Med Chem. 2020. PMID: 33226222
Fragment-to-Lead Medicinal Chemistry Publications in 2018.
Erlanson DA, de Esch IJP, Jahnke W, Johnson CN, Mortenson PN. Erlanson DA, et al. Among authors: de esch ijp. J Med Chem. 2020 May 14;63(9):4430-4444. doi: 10.1021/acs.jmedchem.9b01581. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31913033
Histamine H3 receptor agonists.
De Esch IJ, Belzar KJ. De Esch IJ, et al. Mini Rev Med Chem. 2004 Nov;4(9):955-63. doi: 10.2174/1389557043403134. Mini Rev Med Chem. 2004. PMID: 15544556 Review.
Molecular interaction fingerprint approaches for GPCR drug discovery.
Vass M, Kooistra AJ, Ritschel T, Leurs R, de Esch IJ, de Graaf C. Vass M, et al. Among authors: de esch ij. Curr Opin Pharmacol. 2016 Oct;30:59-68. doi: 10.1016/j.coph.2016.07.007. Epub 2016 Jul 29. Curr Opin Pharmacol. 2016. PMID: 27479316 Review.
158 results