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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 4
1982 2
1984 2
1985 3
1986 4
1987 2
1988 3
1990 2
1991 3
1992 4
1993 4
1994 3
1995 7
1996 9
1997 5
1998 3
1999 6
2000 6
2001 6
2002 6
2003 4
2004 15
2005 15
2006 16
2007 14
2008 19
2009 21
2010 29
2011 35
2012 34
2013 27
2014 34
2015 25
2016 26
2017 25
2018 42
2019 26
2020 24
2021 25
2022 12
2023 15

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Article type

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Search Results

500 results

Results by year

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Page 1
Impact of GPCR Structures on Drug Discovery.
Congreve M, de Graaf C, Swain NA, Tate CG. Congreve M, et al. Among authors: de graaf c. Cell. 2020 Apr 2;181(1):81-91. doi: 10.1016/j.cell.2020.03.003. Cell. 2020. PMID: 32243800 Free article. Review.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: de graaf c. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free article. Clinical Trial.
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.
Jacquelot N, Seillet C, Wang M, Pizzolla A, Liao Y, Hediyeh-Zadeh S, Grisaru-Tal S, Louis C, Huang Q, Schreuder J, Souza-Fonseca-Guimaraes F, de Graaf CA, Thia K, Macdonald S, Camilleri M, Luong K, Zhang S, Chopin M, Molden-Hauer T, Nutt SL, Umansky V, Ciric B, Groom JR, Foster PS, Hansbro PM, McKenzie ANJ, Gray DHD, Behren A, Cebon J, Vivier E, Wicks IP, Trapani JA, Munitz A, Davis MJ, Shi W, Neeson PJ, Belz GT. Jacquelot N, et al. Among authors: de graaf ca. Nat Immunol. 2021 Jul;22(7):851-864. doi: 10.1038/s41590-021-00943-z. Epub 2021 Jun 7. Nat Immunol. 2021. PMID: 34099918 Free PMC article.
Modulators of CXCR4 and CXCR7/ACKR3 Function.
Adlere I, Caspar B, Arimont M, Dekkers S, Visser K, Stuijt J, de Graaf C, Stocks M, Kellam B, Briddon S, Wijtmans M, de Esch I, Hill S, Leurs R. Adlere I, et al. Among authors: de graaf c. Mol Pharmacol. 2019 Dec;96(6):737-752. doi: 10.1124/mol.119.117663. Epub 2019 Sep 23. Mol Pharmacol. 2019. PMID: 31548340 Review.
Editorial: Peptide-binding GPCRs coming of age.
Di Pizio A, Bermudez M, De Graaf C, Jockers R. Di Pizio A, et al. Among authors: de graaf c. Front Endocrinol (Lausanne). 2023 Apr 21;14:1189508. doi: 10.3389/fendo.2023.1189508. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37152971 Free PMC article. No abstract available.
Structural Analysis of Chemokine Receptor-Ligand Interactions.
Arimont M, Sun SL, Leurs R, Smit M, de Esch IJP, de Graaf C. Arimont M, et al. Among authors: de graaf c. J Med Chem. 2017 Jun 22;60(12):4735-4779. doi: 10.1021/acs.jmedchem.6b01309. Epub 2017 Mar 10. J Med Chem. 2017. PMID: 28165741 Free PMC article. Review.
The Landscape of Atypical and Eukaryotic Protein Kinases.
Kanev GK, de Graaf C, de Esch IJP, Leurs R, Würdinger T, Westerman BA, Kooistra AJ. Kanev GK, et al. Among authors: de graaf c. Trends Pharmacol Sci. 2019 Nov;40(11):818-832. doi: 10.1016/ Epub 2019 Oct 31. Trends Pharmacol Sci. 2019. PMID: 31677919 Free article. Review.
500 results