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2017 4
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Pump-Less, Recirculating Organ-on-Chip (rOoC) Platform to Model the Metabolic Crosstalk between Islets and Liver.
Aizenshtadt A, Wang C, Abadpour S, Menezes PD, Wilhelmsen I, Dalmao-Fernandez A, Stokowiec J, Golovin A, Johnsen M, Combriat TMD, Røberg-Larsen H, Gadegaard N, Scholz H, Busek M, Krauss SJK. Aizenshtadt A, et al. Among authors: menezes pd. Adv Healthc Mater. 2024 May;13(13):e2303785. doi: 10.1002/adhm.202303785. Epub 2024 Feb 9. Adv Healthc Mater. 2024. PMID: 38221504
Finally, the platform reproduces known effects of anti-diabetic drugs on-chip. Taken together, the platform provides a basis for functional studies of obesity, T2DM, and MASLD on-chip, as well as for testing potential therapeutic interventions....
Finally, the platform reproduces known effects of anti-diabetic drugs on-chip. Taken together, the platform provides a basis for func …
Cyclodextrins improving the physicochemical and pharmacological properties of antidepressant drugs: a patent review.
Diniz TC, Pinto TCC, Menezes PDP, Silva JC, Teles RBA, Ximenes RCC, Guimarães AG, Serafini MR, Araújo AAS, Quintans Júnior LJ, Almeida JRGDS. Diniz TC, et al. Among authors: menezes pdp. Expert Opin Ther Pat. 2018 Jan;28(1):81-92. doi: 10.1080/13543776.2017.1384816. Epub 2017 Oct 5. Expert Opin Ther Pat. 2018. PMID: 28965471 Review.
Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these drugs, which have a slow onset of action in addition to producing undesirable side effects. Some scientific evidence suggests that cyclodextrins ( …
Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these drugs, which …
Hesperetin-loaded lipid-core nanocapsules in polyamide: a new textile formulation for topical drug delivery.
Menezes PD, Frank LA, Lima BD, de Carvalho YM, Serafini MR, Quintans-Júnior LJ, Pohlmann AR, Guterres SS, Araújo AA. Menezes PD, et al. Int J Nanomedicine. 2017 Mar 15;12:2069-2079. doi: 10.2147/IJN.S124564. eCollection 2017. Int J Nanomedicine. 2017. PMID: 28352176 Free PMC article.
Traditionally, nonsurgical treatments relied on the use of compression therapy, and more recently a variety of flavonoids have been shown to have positive effects. There have also been developments of more effective drug delivery systems using various textiles and n …
Traditionally, nonsurgical treatments relied on the use of compression therapy, and more recently a variety of flavonoids have been shown to …
Eplingiella fruticosa leaf essential oil complexed with β-cyclodextrin produces a superior neuroprotective and behavioral profile in a mice model of Parkinson's disease.
Beserra-Filho JIA, de Macêdo AM, Leão AHFF, Bispo JMM, Santos JR, de Oliveira-Melo AJ, Menezes PDP, Duarte MC, de Souza Araújo AA, Silva RH, Quintans-Júnior LJ, Ribeiro AM. Beserra-Filho JIA, et al. Among authors: menezes pdp. Food Chem Toxicol. 2019 Feb;124:17-29. doi: 10.1016/j.fct.2018.11.056. Epub 2018 Nov 24. Food Chem Toxicol. 2019. PMID: 30481574 Free article.
Antioxidant agents from natural products have shown neuroprotective effects in animal models of PD. Eplingiella fruticosa is an aromatic and medicinal plant of the Lamiaceae family that include culinary herbs. ...Further, EPL-betaCD enhanced this protective effects, …
Antioxidant agents from natural products have shown neuroprotective effects in animal models of PD. Eplingiella fruticosa is an aroma …
Anti-inflammatory activity of the essential oil obtained from Ocimum basilicum complexed with β-cyclodextrin (β-CD) in mice.
Rodrigues LB, Martins AOBPB, Ribeiro-Filho J, Cesário FRAS, E Castro FF, de Albuquerque TR, Fernandes MNM, da Silva BAF, Quintans Júnior LJ, Araújo AAS, Menezes PDP, Nunes PS, Matos IG, Coutinho HDM, Goncalves Wanderley A, de Menezes IRA. Rodrigues LB, et al. Among authors: menezes pdp. Food Chem Toxicol. 2017 Nov;109(Pt 2):836-846. doi: 10.1016/j.fct.2017.02.027. Epub 2017 Feb 22. Food Chem Toxicol. 2017. PMID: 28235614 Free article.
The aim of this study was to investigate the anti-inflammatory effects of the essential oil obtained from O. basilicum complexed with beta - cyclodextrin (OBEO/beta-CD) in mice. ...Our results indicate that conjugation with beta-CD improves the anti-inflammatory effects …
The aim of this study was to investigate the anti-inflammatory effects of the essential oil obtained from O. basilicum complexed with …
Evaluation of the antibacterial and modulatory potential of α-bisabolol, β-cyclodextrin and α-bisabolol/β-cyclodextrin complex.
Oliveira FS, Freitas TS, Cruz RPD, Costa MDS, Pereira RLS, Quintans-Júnior LJ, Andrade TA, Menezes PDP, Sousa BMH, Nunes PS, Serafini MR, Menezes IRA, Araújo AAS, Coutinho HDM. Oliveira FS, et al. Among authors: menezes pdp. Biomed Pharmacother. 2017 Aug;92:1111-1118. doi: 10.1016/j.biopha.2017.06.020. Epub 2017 Jun 12. Biomed Pharmacother. 2017. PMID: 28622712
The results showed that beta-cyclodextrin did not present synergistic effects when combined with the antibiotics. It was found that alpha-bisabolol presented a synergistic effect against S. aureus, when combined with the antibiotic norfloxacin. ...
The results showed that beta-cyclodextrin did not present synergistic effects when combined with the antibiotics. It was found that a …