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2014 1
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15 results

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Page 1
The induction effect of hydroxyurea and metformin on fetal globin in the K562 cell line.
Eini M, Safarpour H, Miri-Moghddam E. Eini M, et al. Mol Med. 2025 Apr 8;31(1):132. doi: 10.1186/s10020-025-01184-8. Mol Med. 2025. PMID: 40200166 Free PMC article.
Notably, the highest levels of gamma-globin expression and Hb F production were observed with HU (100 M), Met (50 M), and HU/Met (100/50 M). This study provides compelling evidence that HU and Met significantly enhance gamma-globin expression and Hb F production …
Notably, the highest levels of gamma-globin expression and Hb F production were observed with HU (100 M), Met (50 M), and HU/Met (1 …
Treatment with Hydroxyurea Leads to Fetal Hemoglobin Reactivation through CA1 and LIN28B Genes: An In Vitro Study.
Parsasefat M, Safarpour H, Nomiri S, Miri-Moghaddam E. Parsasefat M, et al. Hemoglobin. 2022 May;46(3):153-159. doi: 10.1080/03630269.2022.2041434. Epub 2022 May 4. Hemoglobin. 2022. PMID: 35506261
Hydroxyurea (HU) is an effective drug to increase fetal gamma-globin gene (Hb F) expression, replacing the missing adult beta-globin gene. The mechanism of Hb F induction by HU and improvement in clinical symptoms are still poorly understood. ...The CA1 expression s …
Hydroxyurea (HU) is an effective drug to increase fetal gamma-globin gene (Hb F) expression, replacing the missing adult beta-globin …
Comparing newly developed SNP barcode panels with microsatellites to explore population genetics of malaria parasites in the Peruvian Amazon.
Cabrera-Sosa L, Safarpour M, Kattenberg JH, Ramirez R, Vinetz J, Rosanas-Urgell A, Gamboa D, Delgado-Ratto C. Cabrera-Sosa L, et al. bioRxiv [Preprint]. 2024 Sep 9:2024.09.09.611954. doi: 10.1101/2024.09.09.611954. bioRxiv. 2024. Update in: Front Genet. 2024 Dec 19;15:1488109. doi: 10.3389/fgene.2024.1488109. PMID: 39314390 Free PMC article. Updated. Preprint.
Pairwise genetic differentiation (fixation index, F (ST) ) was also comparable: F (ST-MS) = 0.04 - 0.14 and F (ST-SNP) = 0.03 - 0.12 (p = 0.34 - 0.85). ...In addition, Pf genetic diversity trends ( He (MS) = 0 - 0.48 p = 0.03 - 1; He (SNP) = 0 - 0.09, p = 0.0 …
Pairwise genetic differentiation (fixation index, F (ST) ) was also comparable: F (ST-MS) = 0.04 - 0.14 and F (ST-SNP) …
Comparing newly developed SNP barcode panels with microsatellites to explore population genetics of malaria parasites in the Peruvian Amazon.
Cabrera-Sosa L, Safarpour M, Kattenberg JH, Ramirez R, Vinetz JM, Rosanas-Urgell A, Gamboa D, Delgado-Ratto C. Cabrera-Sosa L, et al. Front Genet. 2024 Dec 19;15:1488109. doi: 10.3389/fgene.2024.1488109. eCollection 2024. Front Genet. 2024. PMID: 39748949 Free PMC article.

P. vivax pairwise genetic differentiation (fixation index, F(ST)) was also comparable: F(ST-MS) = 0.04-0.14 and F(ST-SNP) = 0.03-0.12 (pairwise p > 0.05). In addition, P. falciparum genetic diversity trends (He (MS) = 0-0.48, p < 0.05; He (SNP) = 0-0.09

…
P. vivax pairwise genetic differentiation (fixation index, F(ST)) was also comparable: F(ST-MS) = 0.04-0.14 and F(ST-SN …
Functionalized Metallic 2D Transition Metal Dichalcogenide-Based Solid-State Electrolyte for Flexible All-Solid-State Supercapacitors.
Bagheri A, Bellani S, Beydaghi H, Eredia M, Najafi L, Bianca G, Zappia MI, Safarpour M, Najafi M, Mantero E, Sofer Z, Hou G, Pellegrini V, Feng X, Bonaccorso F. Bagheri A, et al. ACS Nano. 2022 Oct 25;16(10):16426-16442. doi: 10.1021/acsnano.2c05640. Epub 2022 Oct 4. ACS Nano. 2022. PMID: 36194759 Free PMC article.
The terminal sulfonate groups in f-NbS(2) nanoflakes interact with the sulfonic acid groups of SPEEK by forming a robust hydrogen bonding network. ...The use of our solid-state electrolyte in combination with proton-conducting SPEEK binder and carbonaceous electrode materi …
The terminal sulfonate groups in f-NbS(2) nanoflakes interact with the sulfonic acid groups of SPEEK by forming a robust hydrogen bon …
Unlocking Therapeutic Potential: Enhanced shRNA Delivery with Tat Peptide in the Human Respiratory Syncytial Virus Treatment.
Amiri Zadeh Fard S, Abuei H, Behzad Behbahani A, Rafiei Dehbidi G, Zare F, Nejabat M, Safarpour A, Farhadi A. Amiri Zadeh Fard S, et al. Adv Pharm Bull. 2024 Oct;14(3):696-704. doi: 10.34172/apb.2024.045. Epub 2024 May 14. Adv Pharm Bull. 2024. PMID: 39494251 Free PMC article.
PURPOSE: This research investigated the development of short hairpin RNA (shRNA) molecules designed to target specific regions of the human respiratory syncytial virus (HRSV) M and F genes. The study aimed to assess the therapeutic potential of these shRNAs and evaluate th …
PURPOSE: This research investigated the development of short hairpin RNA (shRNA) molecules designed to target specific regions of the human …
IL-17 Genetic Variations Increase The Risk of Cirrhotic/Hepatocellular Carcinoma in Patients with Hepatitis B Virus Infection.
Gheshlaghi A, Haghshenas MR, Safarpour AR, Hosseini SY, Fattahi MR, Sarvari J. Gheshlaghi A, et al. Iran J Immunol. 2021 Jun;18(2):130-140. doi: 10.22034/iji.2021.88020.1852. Iran J Immunol. 2021. PMID: 34190694 Free article.
MATERIALS AND METHODS: 300 chronic HBV infections with Cirrhotic/Hepatocellular carcinoma(C/HCC), chronic active (CA), and asymptomatic carrier (AC) and 38 individuals whose infection was spontaneously cleared (SC) were enrolled. Genomic DNA was extracted, and IL-17A/F and …
MATERIALS AND METHODS: 300 chronic HBV infections with Cirrhotic/Hepatocellular carcinoma(C/HCC), chronic active (CA), and asymptomatic carr …
15 results