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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1969 1
1975 2
1976 3
1977 2
1978 4
1979 1
1980 1
1981 1
1982 2
1983 3
1984 3
1985 2
1986 5
1987 7
1988 5
1989 7
1990 7
1991 8
1992 16
1993 13
1994 20
1995 16
1996 14
1997 18
1998 32
1999 28
2000 29
2001 30
2002 40
2003 22
2004 35
2005 46
2006 33
2007 32
2008 38
2009 41
2010 48
2011 44
2012 38
2013 44
2014 50
2015 53
2016 45
2017 58
2018 58
2019 60
2020 55
2021 55
2022 8
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1,062 results
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Page 1
Bone development.
Berendsen AD, Olsen BR. Berendsen AD, et al. Bone. 2015 Nov;80:14-18. doi: 10.1016/j.bone.2015.04.035. Bone. 2015. PMID: 26453494 Free PMC article. Review.
This review describes the processes that result in endochondral and intramembranous ossification, the important roles of growth and transcription factors, and the consequences of mutations in some of the genes involved. ...
This review describes the processes that result in endochondral and intramembranous ossification, the important roles of growt …
Angiogenesis and intramembranous osteogenesis.
Percival CJ, Richtsmeier JT. Percival CJ, et al. Dev Dyn. 2013 Aug;242(8):909-22. doi: 10.1002/dvdy.23992. Epub 2013 Jun 27. Dev Dyn. 2013. PMID: 23737393 Free PMC article. Review.
BACKGROUND: Angiogenesis is likely critical for the process of intramembranous osteogenesis; however, the developmental relationship between blood vessels and bone mineralization is not well studied within intramembranous bones. ...RESULTS: We summarize what …
BACKGROUND: Angiogenesis is likely critical for the process of intramembranous osteogenesis; however, the developmental relati …
CD169(+) macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair.
Batoon L, Millard SM, Wullschleger ME, Preda C, Wu AC, Kaur S, Tseng HW, Hume DA, Levesque JP, Raggatt LJ, Pettit AR. Batoon L, et al. Biomaterials. 2019 Mar;196:51-66. doi: 10.1016/j.biomaterials.2017.10.033. Epub 2017 Oct 22. Biomaterials. 2019. PMID: 29107337 Free article.
The impact of CD169(+) macrophage depletion was assessed in two models of bone injury that heal via either intramembranous (tibial injury) or endochondral (internally-plated femoral fracture model) ossification. ...
The impact of CD169(+) macrophage depletion was assessed in two models of bone injury that heal via either intramembranous (tibial in …
Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway.
Zhao SJ, Kong FQ, Jie J, Li Q, Liu H, Xu AD, Yang YQ, Jiang B, Wang DD, Zhou ZQ, Tang PY, Chen J, Wang Q, Zhou Z, Chen Q, Yin GY, Zhang HW, Fan J. Zhao SJ, et al. Theranostics. 2020 Jan 1;10(1):17-35. doi: 10.7150/thno.36930. eCollection 2020. Theranostics. 2020. PMID: 31903103 Free PMC article.
Methods: The tibial monocortical defect model was employed to determine the critical role of macrophage scavenger receptor 1 (MSR1) during intramembranous ossification (IO) in vivo. The potential functions and mechanisms of MSR1 were explored in a co-culture system …
Methods: The tibial monocortical defect model was employed to determine the critical role of macrophage scavenger receptor 1 (MSR1) during …
Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair.
Hu K, Olsen BR. Hu K, et al. J Clin Invest. 2016 Feb;126(2):509-26. doi: 10.1172/JCI82585. Epub 2016 Jan 5. J Clin Invest. 2016. PMID: 26731472 Free PMC article.
Using transgenic mice with osteoblast-specific deletion of Vegfa, we demonstrated that VEGF promoted macrophage recruitment and angiogenic responses in the inflammation phase, and optimal levels of VEGF were required for coupling of angiogenesis and osteogenesis in areas w …
Using transgenic mice with osteoblast-specific deletion of Vegfa, we demonstrated that VEGF promoted macrophage recruitment and angiogenic r …
Hdac-mediated control of endochondral and intramembranous ossification.
Bradley EW, McGee-Lawrence ME, Westendorf JJ. Bradley EW, et al. Crit Rev Eukaryot Gene Expr. 2011;21(2):101-13. doi: 10.1615/critreveukargeneexpr.v21.i2.10. Crit Rev Eukaryot Gene Expr. 2011. PMID: 22077150 Free PMC article. Review.
Bone is a dynamic tissue that forms and regenerates by two processes: endochondral and intramembranous ossification. Chondrocytes and osteoblasts are responsible for producing the extracellular matrices of skeletal tissues. ...
Bone is a dynamic tissue that forms and regenerates by two processes: endochondral and intramembranous ossification. Chondrocy …
The roles of vascular endothelial growth factor in bone repair and regeneration.
Hu K, Olsen BR. Hu K, et al. Bone. 2016 Oct;91:30-8. doi: 10.1016/j.bone.2016.06.013. Epub 2016 Jun 25. Bone. 2016. PMID: 27353702 Free PMC article. Review.
Since bone is a highly vascularized organ and angiogenesis plays an important role in osteogenesis, VEGF also influences skeletal development and postnatal bone repair. ...This review (i) summarizes the roles of VEGF at different stages of bone repair, including the phases …
Since bone is a highly vascularized organ and angiogenesis plays an important role in osteogenesis, VEGF also influences skeletal dev …
Fracture healing in osteoporotic bone.
Cheung WH, Miclau T, Chow SK, Yang FF, Alt V. Cheung WH, et al. Injury. 2016 Jun;47 Suppl 2:S21-6. doi: 10.1016/S0020-1383(16)47004-X. Injury. 2016. PMID: 27338222 Review.
As the world population rises, osteoporotic fracture is an emerging global threat to the well-being of elderly patients. The process of fracture healing by intramembranous ossification or/and endochondral ossification involve many well-orchestrated events inc …
As the world population rises, osteoporotic fracture is an emerging global threat to the well-being of elderly patients. The process of frac …
The biological function of BMAL1 in skeleton development and disorders.
Chen G, Tang Q, Yu S, Xie Y, Sun J, Li S, Chen L. Chen G, et al. Life Sci. 2020 Jul 15;253:117636. doi: 10.1016/j.lfs.2020.117636. Epub 2020 Apr 3. Life Sci. 2020. PMID: 32251631 Review.
Skeletal Bone development is a complex biological process involving intramembranous ossification, endochondral ossification and bone remodeling, as well as specific cells, such as mesenchymal cells, osteoblasts, osteoclasts, chondrocytes, etc. ...
Skeletal Bone development is a complex biological process involving intramembranous ossification, endochondral ossification
SHP2 regulates intramembranous ossification by modifying the TGFbeta and BMP2 signaling pathway.
Wang L, Huang J, Moore DC, Song Y, Ehrlich MG, Yang W. Wang L, et al. Bone. 2019 Mar;120:327-335. doi: 10.1016/j.bone.2018.11.014. Epub 2018 Nov 22. Bone. 2019. PMID: 30471432 Free PMC article.
However, how SHP2 regulates osteoblast differentiation in intramembranous ossification remains incompletely understood. To address this question, we generated a mouse model to ablate SHP2 in the Prrx1-expressing mesenchymal progenitors by using "Cre-loxP"-mediated g …
However, how SHP2 regulates osteoblast differentiation in intramembranous ossification remains incompletely understood. To add …
1,062 results