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198 results

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Page 1
Did you mean miao na jiang (8 results)?
A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity.
Wang X, Fu SQ, Yuan X, Yu F, Ji Q, Tang HW, Li RK, Huang S, Huang PQ, Qin WT, Zuo H, Du C, Yao LL, Li H, Li J, Li DX, Yang Y, Xiao SY, Tulamaiti A, Wang XF, Dai CH, Zhang X, Jiang SH, Hu LP, Zhang XL, Zhang ZG. Wang X, et al. Mol Cell. 2024 Feb 15;84(4):760-775.e7. doi: 10.1016/j.molcel.2023.12.015. Epub 2024 Jan 11. Mol Cell. 2024. PMID: 38215751
CD8(+) T cells accumulate intracellular 5-HT for serotonylation through both synthesis by tryptophan hydroxylase 1 (TPH1) and uptake from the extracellular compartment via serotonin transporter (SERT). Monoamine oxidase A (MAOA) degrades 5-HT and acts as an intrinsi …
CD8(+) T cells accumulate intracellular 5-HT for serotonylation through both synthesis by tryptophan hydroxylase 1 (TPH1) and uptake from th …
Curcumin Reprograms TAMs from a Protumor Phenotype towards an Antitumor Phenotype via Inhibiting MAO-A/STAT6 Pathway.
Jiang M, Qi Y, Huang W, Lin Y, Li B. Jiang M, et al. Cells. 2022 Nov 2;11(21):3473. doi: 10.3390/cells11213473. Cells. 2022. PMID: 36359867 Free PMC article.
Mechanistically, the repolarization of TAMs may be attributed to the inhibition of monoamine oxidase A (MAO-A)/STAT6 signaling after curcumin treatment. Collectively, our results show that the anticancer effects of curcumin could be explained by reprog …
Mechanistically, the repolarization of TAMs may be attributed to the inhibition of monoamine oxidase A (MAO-A)/S …
FAP expression in adipose tissue macrophages promotes obesity and metabolic inflammation.
Wu Y, Wu C, Shi T, Cai Q, Wang T, Xiong Y, Zhang Y, Jiang W, Lu M, Chen Z, Chen J, Wang J, He R. Wu Y, et al. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2303075120. doi: 10.1073/pnas.2303075120. Epub 2023 Dec 15. Proc Natl Acad Sci U S A. 2023. PMID: 38100414 Free PMC article.
Such enhanced energy expenditure is associated with increased levels of norepinephrine (NE) and lipolysis in white adipose tissues, likely due to decreased expression of monoamine oxidase, a NE degradation enzyme, by Fap(-/-) ATM. Collectively, our study identifies …
Such enhanced energy expenditure is associated with increased levels of norepinephrine (NE) and lipolysis in white adipose tissues, likely d …
Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice.
Jiang SH, Li J, Dong FY, Yang JY, Liu DJ, Yang XM, Wang YH, Yang MW, Fu XL, Zhang XX, Li Q, Pang XF, Huo YM, Li J, Zhang JF, Lee HY, Lee SJ, Qin WX, Gu JR, Sun YW, Zhang ZG. Jiang SH, et al. Gastroenterology. 2017 Jul;153(1):277-291.e19. doi: 10.1053/j.gastro.2017.03.008. Epub 2017 Mar 15. Gastroenterology. 2017. PMID: 28315323
Sirt1/FoxO1-Associated MAO-A Upregulation Promotes Depressive-Like Behavior in Transgenic Mice Expressing Human A53T alpha-Synuclein.
Li Y, Jiao Q, Du X, Jiang H. Li Y, et al. ACS Chem Neurosci. 2020 Nov 18;11(22):3838-3848. doi: 10.1021/acschemneuro.0c00628. Epub 2020 Nov 6. ACS Chem Neurosci. 2020. PMID: 33155799
Mechanistically, Sirt1 was downregulated which lead to an increase in FoxO1 acetylation, which subsequently increased the transcription of MAO-A. Activation of Sirt1 by resveratrol or inhibition of MAO-A by moclobemide administration could restore brai …
Mechanistically, Sirt1 was downregulated which lead to an increase in FoxO1 acetylation, which subsequently increased the transcription of …
Inhibitive activities detection of monoamine oxidases (MAO) A and B inhibitors in human liver MAO incubations by UPLC-ESI-MS/MS.
Jiang B, Li S, Liu W, Yang Y, Chen W, He D, Cheng X, Wang Z, Chen W, Wang C. Jiang B, et al. J Pharm Biomed Anal. 2015 Nov 10;115:283-91. doi: 10.1016/j.jpba.2015.07.029. Epub 2015 Jul 26. J Pharm Biomed Anal. 2015. PMID: 26263056
A sensitive UPLC-ESI-MS/MS method was developed for determining and screening of inhibitors of monoamine oxidase (MAO) by using mix MAO enzymes prepared from human liver. 5-Hydroxytryptamine (5-HT) and 2-phenethylamine (2-PEA) were used as substrates for MAO- …
A sensitive UPLC-ESI-MS/MS method was developed for determining and screening of inhibitors of monoamine oxidase (MAO) by usin …
Decreased monoamine oxidase (MAO) activity and MAO-A expression as diagnostic indicators of human esophageal cancers.
Yang B, Jiang J, Du H, Geng G, Jiang Z, Yao C, Zhang Q, Jin L. Yang B, et al. Biomarkers. 2009 Dec;14(8):624-9. doi: 10.3109/13547500903207688. Biomarkers. 2009. PMID: 19740022
Our studies showed that the activity of monoamine oxidase (MAO) and the expression of MAO-A were strikingly decreased in the tumour tissues of 48 (96%) and 44 (88%) patients, respectively. These results suggest that the activity of MAO and the expressi …
Our studies showed that the activity of monoamine oxidase (MAO) and the expression of MAO-A were strikingly decr …
Association of COMT rs4680 and MAO-B rs1799836 polymorphisms with levodopa-induced dyskinesia in Parkinson's disease-a meta-analysis.
Yin Y, Liu Y, Xu M, Zhang X, Li C. Yin Y, et al. Neurol Sci. 2021 Oct;42(10):4085-4094. doi: 10.1007/s10072-021-05509-3. Epub 2021 Aug 4. Neurol Sci. 2021. PMID: 34346015 Review.
BACKGROUND AND PURPOSE: Polymorphisms of the catechol-O-methyl transferase (COMT) or monoamine oxidase B (MAO-B) genes may affect the occurrence of dyskinesia in Parkinson's disease (PD) patients. ...
BACKGROUND AND PURPOSE: Polymorphisms of the catechol-O-methyl transferase (COMT) or monoamine oxidase B (MAO-B) genes may aff …
The effects of tranylcypromine on osteoclastogenesis in vitro and in vivo.
Liu Z, Yang K, Yan X, Wang T, Jiang T, Zhou Q, Qi J, Qian N, Zhou H, Chen B, Huang P, Guo L, Zhang X, Xu X, Jiang M, Deng L. Liu Z, et al. FASEB J. 2019 Sep;33(9):9828-9841. doi: 10.1096/fj.201802242RR. Epub 2019 Jul 10. FASEB J. 2019. PMID: 31291555
Tranylcypromine (TCP), an irreversible inhibitor of monoamine oxidase (MAO), has been used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders. ...Furthermore, the effects of MAO-A knockdown on OC different …
Tranylcypromine (TCP), an irreversible inhibitor of monoamine oxidase (MAO), has been used as an antidepressant and anxiolytic …
198 results