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The following term was not found in PubMed: mirnader
Page 1
HIF‑1α in myocardial ischemia‑reperfusion injury (Review).
Zheng J, Chen P, Zhong J, Cheng Y, Chen H, He Y, Chen C. Zheng J, et al. Mol Med Rep. 2021 May;23(5):352. doi: 10.3892/mmr.2021.11991. Epub 2021 Mar 24. Mol Med Rep. 2021. PMID: 33760122 Free PMC article. Review.
Myocardial ischemia-reperfusion injury (MIRI) is a severe injury to the ischemic myocardium following the recovery of blood flow. ...The present review summarizes the roles and associated mechanisms of action of HIF-1alpha in MIRI. In addition, HIF-1alpha-associated …
Myocardial ischemia-reperfusion injury (MIRI) is a severe injury to the ischemic myocardium following the recovery of blood flow. ... …
The PINK1/Parkin signaling pathway-mediated mitophagy: a forgotten protagonist in myocardial ischemia/reperfusion injury.
Zhao X, Wang Z, Wang L, Jiang T, Dong D, Sun M. Zhao X, et al. Pharmacol Res. 2024 Nov;209:107466. doi: 10.1016/j.phrs.2024.107466. Epub 2024 Oct 15. Pharmacol Res. 2024. PMID: 39419133 Free article. Review.
Myocardial ischemia causes extensive damage, further exacerbated by reperfusion, a phenomenon called myocardial ischemia/reperfusion injury (MIRI). Nowadays, the pathological mechanisms of MIRI have received extensive attention. ...Therefore, exploring the associati …
Myocardial ischemia causes extensive damage, further exacerbated by reperfusion, a phenomenon called myocardial ischemia/reperfusion injury …
The pathological mechanisms and potential therapeutic drugs for myocardial ischemia reperfusion injury.
Zhang S, Yan F, Luan F, Chai Y, Li N, Wang YW, Chen ZL, Xu DQ, Tang YP. Zhang S, et al. Phytomedicine. 2024 Jul;129:155649. doi: 10.1016/j.phymed.2024.155649. Epub 2024 Apr 16. Phytomedicine. 2024. PMID: 38653154 Review.
Therefore, it is of great significance to prevent and treat MIRI. PURPOSE: MIRI is an important factor affecting the prognosis of patients, and there is no specific in-clinic treatment plan. ...These efforts will facilitate the emergence of fresh perspectives for th …
Therefore, it is of great significance to prevent and treat MIRI. PURPOSE: MIRI is an important factor affecting the prognosis …
The role of PI3K/AKT signaling pathway in myocardial ischemia-reperfusion injury.
Deng RM, Zhou J. Deng RM, et al. Int Immunopharmacol. 2023 Oct;123:110714. doi: 10.1016/j.intimp.2023.110714. Epub 2023 Jul 29. Int Immunopharmacol. 2023. PMID: 37523969 Review.
However, reperfusion may lead to further myocardial damage, known as myocardial ischemia/reperfusion injury (MIRI). There are currently no effective clinical treatments for MIRI. The PI3K/Akt signaling pathway is involved in cardiovascular health and disease and pla …
However, reperfusion may lead to further myocardial damage, known as myocardial ischemia/reperfusion injury (MIRI). There are current …
Ferroptosis: Opportunities and Challenges in Myocardial Ischemia-Reperfusion Injury.
Zhao WK, Zhou Y, Xu TT, Wu Q. Zhao WK, et al. Oxid Med Cell Longev. 2021 Oct 23;2021:9929687. doi: 10.1155/2021/9929687. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34725566 Free PMC article. Review.
Myocardial ischemia-reperfusion injury (MIRI) is an unavoidable risk event for acute myocardial infarction. Ferroptosis is closely associated with MIRI, and this relationship is discussed in detail here. This review systematically summarizes the process of ferroptos …
Myocardial ischemia-reperfusion injury (MIRI) is an unavoidable risk event for acute myocardial infarction. Ferroptosis is closely as …
Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway.
Yan J, Li Z, Liang Y, Yang C, Ou W, Mo H, Tang M, Chen D, Zhong C, Que D, Feng L, Xiao H, Song X, Yang P. Yan J, et al. Food Funct. 2023 Nov 13;14(22):10052-10068. doi: 10.1039/d3fo02633g. Food Funct. 2023. PMID: 37861458
Therefore, there is an urgent requirement to find more therapeutic solutions for MIRI. Recently, ferroptosis, which is characterized by lipid peroxidation, was considered a critical contributor to MIRI. ...Results: TTC-Evans blue staining showed that FX reduced the …
Therefore, there is an urgent requirement to find more therapeutic solutions for MIRI. Recently, ferroptosis, which is characterized …
Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review).
He J, Liu D, Zhao L, Zhou D, Rong J, Zhang L, Xia Z. He J, et al. Exp Ther Med. 2022 Jun;23(6):430. doi: 10.3892/etm.2022.11357. Epub 2022 May 6. Exp Ther Med. 2022. PMID: 35607376 Free PMC article. Review.
However, when the interrupted myocardial blood supply is recovered within a certain period of time, it causes more serious damage to the original ischemic myocardium; this is known as myocardial ischemia/reperfusion injury (MIRI). The pathophysiological mechanisms leading …
However, when the interrupted myocardial blood supply is recovered within a certain period of time, it causes more serious damage to the ori …
Single-cell profile reveals the landscape of cardiac immunity and identifies a cardio-protective Ym-1hi neutrophil in myocardial ischemia-reperfusion injury.
Dong Y, Kang Z, Zhang Z, Zhang Y, Zhou H, Liu Y, Shuai X, Li J, Yin L, Wang X, Ma Y, Fan H, Jiang F, Lin Z, Ding C, Yun Jin K, Sarapultsev A, Li F, Zhang G, Xie T, Yin C, Cheng X, Luo S, Liu Y, Hu D. Dong Y, et al. Sci Bull (Beijing). 2024 Apr 15;69(7):949-967. doi: 10.1016/j.scib.2024.02.003. Epub 2024 Feb 7. Sci Bull (Beijing). 2024. PMID: 38395651 Free article.
Myocardial ischemia-reperfusion injury (MIRI) is a major hindrance to the success of cardiac reperfusion therapy. Although increased neutrophil infiltration is a hallmark of MIRI, the subtypes and alterations of neutrophils in this process remain unclear. Here, we p …
Myocardial ischemia-reperfusion injury (MIRI) is a major hindrance to the success of cardiac reperfusion therapy. Although increased …
Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia-reperfusion injury.
Zhong C, Dong H, Ma Y, Zhuang B, Shi H, Hong L. Zhong C, et al. FASEB J. 2024 Nov 15;38(21):e70164. doi: 10.1096/fj.202401056R. FASEB J. 2024. PMID: 39520298
Myocardial ischemia-reperfusion injury (MIRI) is a significant risk factor for acute myocardial infarction and is closely associated with ferroptosis. ...This study reveals the importance of ferroptosis-related genes in MIRI through integrated bioinformatics and exp …
Myocardial ischemia-reperfusion injury (MIRI) is a significant risk factor for acute myocardial infarction and is closely associated …
Pharmacological upregulation of macrophage-derived itaconic acid by pubescenoside C attenuated myocardial ischemia-reperfusion injury.
Chen S, Yao H, Lou Y, Wang H, Xie B, Wu J, Qi X, Wang Y, Wu P, Zhang R, Liu Z, Cheng Y. Chen S, et al. J Adv Res. 2025 Aug;74:571-587. doi: 10.1016/j.jare.2024.09.024. Epub 2024 Sep 30. J Adv Res. 2025. PMID: 39357647 Free PMC article.
Macrophages play a pivotal role in MIRI pathophysiology, exhibiting dynamic inflammatory and resolutive functions. Macrophage polarization and metabolism are intricately linked to MIRI, presenting potential therapeutic targets. Pubescenoside C (PBC) from Ilex pubesc …
Macrophages play a pivotal role in MIRI pathophysiology, exhibiting dynamic inflammatory and resolutive functions. Macrophage polariz …
3,322 results