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Page 1
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB; LEADER Steering Committee; LEADER Trial Investigators. Marso SP, et al. N Engl J Med. 2016 Jul 28;375(4):311-22. doi: 10.1056/NEJMoa1603827. Epub 2016 Jun 13. N Engl J Med. 2016. PMID: 27295427 Free PMC article. Clinical Trial.
The primary outcome occurred in significantly fewer patients in the liraglutide group (608 of 4668 patients [13.0%]) than in the placebo group (694 of 4672 [14.9%]) (hazard ratio, 0.87; 95% confidence interval [CI], 0.78 to 0.97; P<0.001 for noninferiority; P=0.0 …
The primary outcome occurred in significantly fewer patients in the liraglutide group (608 of 4668 patients [13.0%]) than in the placebo gro …
Liraglutide and Renal Outcomes in Type 2 Diabetes.
Mann JFE, Ørsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, Tornøe K, Zinman B, Buse JB; LEADER Steering Committee and Investigators. Mann JFE, et al. N Engl J Med. 2017 Aug 31;377(9):839-848. doi: 10.1056/NEJMoa1616011. N Engl J Med. 2017. PMID: 28854085 Free article. Clinical Trial.
The renal outcome occurred in fewer participants in the liraglutide group than in the placebo group (268 of 4668 patients vs. 337 of 4672; hazard ratio, 0.78; 95% confidence interval [CI], 0.67 to 0.92; P=0.003). This result was driven primarily by the new onset of persist …
The renal outcome occurred in fewer participants in the liraglutide group than in the placebo group (268 of 4668 patients vs. 337 of 4672; h …
Synthesis, antibacterial activity, and quantitative structure-activity relationships of new (Z)-2-(nitroimidazolylmethylene)-3(2H)-benzofuranone derivatives.
Hadj-esfandiari N, Navidpour L, Shadnia H, Amini M, Samadi N, Faramarzi MA, Shafiee A. Hadj-esfandiari N, et al. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6354-63. doi: 10.1016/j.bmcl.2007.09.062. Epub 2007 Sep 21. Bioorg Med Chem Lett. 2007. PMID: 17919903
A new series of (Z)-2-(1-methyl-5-nitroimidazole-2-ylmethylene)-3(2H)-benzofuranones (11a-p) and (Z)-2-(1-methyl-4-nitroimidazole-5-ylmethylene)-3(2H)-benzofuranones (12a-m) were synthesized and assayed for their antibacterial activity against Gram-positive and G …
A new series of (Z)-2-(1-methyl-5-nitroimidazole-2-ylmethylene)-3(2H)-benzofuranones (11a-p) and (Z)-2-(1-methyl-4-nitroimidazole-5-y …
Design, preparation and biological evaluation of a 177Lu-labeled somatostatin receptor antagonist for targeted therapy of neuroendocrine tumors.
Behnammanesh H, Jokar S, Erfani M, Geramifar P, Sabzevari O, Amini M, Mazidi SM, Hajiramezanali M, Beiki D. Behnammanesh H, et al. Bioorg Chem. 2020 Jan;94:103381. doi: 10.1016/j.bioorg.2019.103381. Epub 2019 Oct 22. Bioorg Chem. 2020. PMID: 31662215
The best docked peptide-chelator conjugate (DOTA-p-Cl-Phe-Cyclo(d-Cys-l-BzThi-d-Aph-Lys-Thr-Cys)-d-Tyr-NH(2)) (DOTA-Peptide 2) was synthesized using the Fmoc solid-phase method. ...Effective tumor uptake of 7.3% ID/g (percentage of injected dose per gram of tumor) a …
The best docked peptide-chelator conjugate (DOTA-p-Cl-Phe-Cyclo(d-Cys-l-BzThi-d-Aph-Lys-Thr-Cys)-d-Tyr-NH(2)) (DOTA-Peptide 2) was sy …
Isolation of Enterococcus faecalis pathogenic genes isolated from oral infection by the effect of ionic liquids based on amino acid and its expression by real-time PCR.
Bonyadi P, Amini K. Bonyadi P, et al. Folia Microbiol (Praha). 2022 Oct;67(5):777-784. doi: 10.1007/s12223-022-00972-7. Epub 2022 May 19. Folia Microbiol (Praha). 2022. PMID: 35588041
Amino-acid-based ionic liquids can also reduce biofilm production at sub-MIC concentrations (P < 0.05), and changes in cytotoxicity at different concentrations and over time are significant (P-value < 0.001). ...

Amino-acid-based ionic liquids can also reduce biofilm production at sub-MIC concentrations (P < 0.05), and changes in cytotoxicit

…
Preparation and Antibacterial Activity Evaluation of 18-β-glycyrrhetinic Acid Loaded PLGA Nanoparticles.
Darvishi B, Manoochehri S, Kamalinia G, Samadi N, Amini M, Mostafavi SH, Maghazei S, Atyabi F, Dinarvand R. Darvishi B, et al. Iran J Pharm Res. 2015 Spring;14(2):373-83. Iran J Pharm Res. 2015. PMID: 25901144 Free PMC article.
GLA loaded PLGA nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanoparticles was examined against different gram-negative and gram-positive bacteria. The antiba …
GLA loaded PLGA nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacteri …
Preclinical study of a new 177Lu-labeled somatostatin receptor antagonist in HT-29 human colorectal cancer cells.
Behnammanesh H, Erfani M, Hajiramezanali M, Jokar S, Geramifar P, Sabzevari O, Amini M, Mazidi SM, Beiki D. Behnammanesh H, et al. Asia Ocean J Nucl Med Biol. 2020 Spring;8(2):109-115. doi: 10.22038/AOJNMB.2020.44432.1299. Asia Ocean J Nucl Med Biol. 2020. PMID: 32714998 Free PMC article.
METHODS: DOTA conjugated antagonistic peptide with the sequence of p-Cl-Phe-Cyclo(D-Cys-L-BzThi-D-Aph-Lys-Thr-Cys)-D-Tyr-NH2 (DOTA-Peptide 2) was labeled with (177)Lu. ...The desired dissociation constant (K(d) =11.14 nM) and effective tumor uptake (10.89 percentage of inj …
METHODS: DOTA conjugated antagonistic peptide with the sequence of p-Cl-Phe-Cyclo(D-Cys-L-BzThi-D-Aph-Lys-Thr-Cys)-D-Tyr-NH2 (DOTA-Pe …
Effects of fixed orthodontic treatment on nickel and chromium levels in gingival crevicular fluid as a novel systemic biomarker of trace elements: A longitudinal study.
Amini F, Shariati M, Sobouti F, Rakhshan V. Amini F, et al. Am J Orthod Dentofacial Orthop. 2016 May;149(5):666-72. doi: 10.1016/j.ajodo.2015.10.023. Am J Orthod Dentofacial Orthop. 2016. PMID: 27131248
RESULTS: The gingival index worsened over time (chi-square test, P <0.001). The mean nickel levels were 3.894 1.442, 5.913 2.735, and 19.810 8.452 mug per gram, respectively, at baseline, month 1, and month 6. Chromium concentrations were 1.978 0.721, 4.1 …
RESULTS: The gingival index worsened over time (chi-square test, P <0.001). The mean nickel levels were 3.894 1.442, 5.913 2.7 …
Evaluation of febrile neutropenia in patients undergoing hematopoietic stem cell transplantation.
Amini S, Hadjibabaie M, Jahangard-Rafsanjani Z, Ashuri A, Torkamandi H, Ghavamzadeh A. Amini S, et al. Acta Med Iran. 2014;52(1):38-42. Acta Med Iran. 2014. PMID: 24658984 Free article.
Microbiologic documents showed that the relative frequencies of gram positive and gram negative bacteria were 62.5% and 37.5%, respectively. The hospital stay duration was directly related to the numbers of fever episodes (P<0.0001).The rate of febrile epi …
Microbiologic documents showed that the relative frequencies of gram positive and gram negative bacteria were 62.5% and 37.5%, …