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81 results

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Page 1
The ear of the Sima de los Huesos hominins (Atapuerca, Spain).
Conde-Valverde M, Martínez I, Quam R, Arsuaga JL. Conde-Valverde M, et al. Anat Rec (Hoboken). 2024 Jul;307(7):2410-2424. doi: 10.1002/ar.25181. Epub 2023 Feb 24. Anat Rec (Hoboken). 2024. PMID: 36825485 Free article.
As in other cranial structures, the ear region in the Sima de los Huesos show a mosaic evolutionary pattern that includes primitive traits, others shared exclusively with Neandertals, and others that are specific to the Sima de los Huesos hominins. Neandertal …
As in other cranial structures, the ear region in the Sima de los Huesos show a mosaic evolutionary pattern that includes primitive t …
Epigenetic Alterations in Bladder Cancer.
Porten SP. Porten SP. Curr Urol Rep. 2018 Oct 24;19(12):102. doi: 10.1007/s11934-018-0861-5. Curr Urol Rep. 2018. PMID: 30357502 Review.
RECENT FINDINGS: Epigenetic alterations are overall shared across various grades and stages of bladder cancer. High grade invasive tumors demonstrate a greater degree and intensity of methylation and may have a unique methylation pattern. ...
RECENT FINDINGS: Epigenetic alterations are overall shared across various grades and stages of bladder cancer. High grade invasive tu …
Predicting Mitochondrial Dynamic Behavior in Genetically Defined Neurodegenerative Diseases.
Dorn GW 2nd, Dang X. Dorn GW 2nd, et al. Cells. 2022 Mar 19;11(6):1049. doi: 10.3390/cells11061049. Cells. 2022. PMID: 35326500 Free PMC article. Review.
In addition to mechanisms and concepts, we explore in detail different technical approaches for measuring mitochondrial dynamic dysfunction in vitro, describe how results from tissue culture studies may be applied to a better understanding of mitochondrial dysdynamism in human ne …
In addition to mechanisms and concepts, we explore in detail different technical approaches for measuring mitochondrial dynamic dysfunction …
Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins.
Meyer M, Arsuaga JL, de Filippo C, Nagel S, Aximu-Petri A, Nickel B, Martínez I, Gracia A, Bermúdez de Castro JM, Carbonell E, Viola B, Kelso J, Prüfer K, Pääbo S. Meyer M, et al. Nature. 2016 Mar 24;531(7595):504-7. doi: 10.1038/nature17405. Epub 2016 Mar 14. Nature. 2016. PMID: 26976447
A unique assemblage of 28 hominin individuals, found in Sima de los Huesos in the Sierra de Atapuerca in Spain, has recently been dated to approximately 430,000 years ago. An interesting question is how these Middle Pleistocene hominins were related to those who lived in t …
A unique assemblage of 28 hominin individuals, found in Sima de los Huesos in the Sierra de Atapuerca in Spain, has recently been dat …
Hexahydrocannabinol: pharmacokinetics, systemic toxicity, and acute behavioral effects in Wistar rats.
Šíchová K, Mallarino B, Janečková L, Palivec P, Vágnerová M, Vejmola Č, Nikolič M, Ladislavová L, Mazochová K, Ryšánek P, Šíma M, Šafanda A, Hiep BQ, Koutrouli IRA, Kuchař M, Páleníček T. Šíchová K, et al. Int J Neuropsychopharmacol. 2025 Aug 1;28(8):pyaf041. doi: 10.1093/ijnp/pyaf041. Int J Neuropsychopharmacol. 2025. PMID: 40643195 Free PMC article.
Macrophage immunomodulation in chronic osteolytic diseases-the case of periodontitis.
Sima C, Viniegra A, Glogauer M. Sima C, et al. J Leukoc Biol. 2019 Mar;105(3):473-487. doi: 10.1002/JLB.1RU0818-310R. Epub 2018 Nov 19. J Leukoc Biol. 2019. PMID: 30452781 Free PMC article. Review.
Periodontitis (PD) is a chronic osteolytic disease that shares pathogenic inflammatory features with other conditions associated with nonresolving inflammation. ...
Periodontitis (PD) is a chronic osteolytic disease that shares pathogenic inflammatory features with other conditions associated with …
Tarsals from the Sima de los Huesos Middle Pleistocene site (Atapuerca, Burgos, Spain).
Pablos A, Arsuaga JL. Pablos A, et al. Anat Rec (Hoboken). 2024 Jul;307(7):2635-2664. doi: 10.1002/ar.25425. Epub 2024 Mar 13. Anat Rec (Hoboken). 2024. PMID: 38477186 Free article.
Here, we provide a complete, updated, and illustrated inventory, as well as a comprehensive study, of the tarsals (rearfoot) recovered from the Middle Pleistocene site of Sima de los Huesos (SH, Atapuerca, Spain) in comparison to other Homo comparative samples, both extant …
Here, we provide a complete, updated, and illustrated inventory, as well as a comprehensive study, of the tarsals (rearfoot) recovered from …
A mitochondrial genome sequence of a hominin from Sima de los Huesos.
Meyer M, Fu Q, Aximu-Petri A, Glocke I, Nickel B, Arsuaga JL, Martínez I, Gracia A, de Castro JM, Carbonell E, Pääbo S. Meyer M, et al. Nature. 2014 Jan 16;505(7483):403-6. doi: 10.1038/nature12788. Epub 2013 Dec 4. Nature. 2014. PMID: 24305051
The skeletal remains share a number of morphological features with fossils classified as Homo heidelbergensis and also display distinct Neanderthal-derived traits. Here we determine an almost complete mitochondrial genome sequence of a hominin from Sima de los Hueso …
The skeletal remains share a number of morphological features with fossils classified as Homo heidelbergensis and also display distin …
Hypoxia-inducible factor 1α is required to establish the larval glycolytic program in Drosophila melanogaster.
Heidarian Y, Fasteen TD, Mungcal L, Buddika K, Mahmoudzadeh NH, Nemkov T, D'Alessandro A, Tennessen JM. Heidarian Y, et al. Mol Metab. 2025 Mar;93:102106. doi: 10.1016/j.molmet.2025.102106. Epub 2025 Jan 31. Mol Metab. 2025. PMID: 39894213 Free PMC article.
CONCLUSIONS: These findings demonstrate that Sima/HIF1alpha is required during embryogenesis to coordinately up-regulate carbohydrate metabolism in preparation for larval growth. Notably, our study also reveals that the Sima/HIF1alpha-dependent gene expression progr …
CONCLUSIONS: These findings demonstrate that Sima/HIF1alpha is required during embryogenesis to coordinately up-regulate carbohydrate …
81 results