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2009 2
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42 results

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Page 1
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Wienke J, Visser LL, Kholosy WM, Keller KM, Barisa M, Poon E, Munnings-Tomes S, Himsworth C, Calton E, Rodriguez A, Bernardi R, van den Ham F, van Hooff SR, Matser YAH, Tas ML, Langenberg KPS, Lijnzaad P, Borst AL, Zappa E, Bergsma FJ, Strijker JGM, Verhoeven BM, Mei S, Kramdi A, Restuadi R, Sanchez-Bernabeu A, Cornel AM, Holstege FCP, Gray JC, Tytgat GAM, Scheijde-Vermeulen MA, Wijnen MHWA, Dierselhuis MP, Straathof K, Behjati S, Wu W, Heck AJR, Koster J, Nierkens S, Janoueix-Lerosey I, de Krijger RR, Baryawno N, Chesler L, Anderson J, Caron HN, Margaritis T, van Noesel MM, Molenaar JJ. Wienke J, et al. Among authors: van hooff sr. Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4. Cancer Cell. 2024. PMID: 38181797 Free PMC article.
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, Hedley A, Yilmaz OH, Rashid M, Bailey P, Biankin AV, Campbell AD, Adams DJ, Barry ST, Steele CW, Medema JP, Sansom OJ. Jackstadt R, et al. Among authors: van hooff sr. Cancer Cell. 2019 Sep 16;36(3):319-336.e7. doi: 10.1016/j.ccell.2019.08.003. Cancer Cell. 2019. PMID: 31526760 Free PMC article.
Transcriptomic subtyping of gastrointestinal malignancies.
de Back TR, van Hooff SR, Sommeijer DW, Vermeulen L. de Back TR, et al. Among authors: van hooff sr. Trends Cancer. 2024 Sep;10(9):842-856. doi: 10.1016/j.trecan.2024.06.007. Epub 2024 Jul 16. Trends Cancer. 2024. PMID: 39019673 Free article. Review.
Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.
Bootsma S, Dings MPG, Kesselaar J, Helderman RFCPA, van Megesen K, Constantinides A, Moreno LF, Stelloo E, Scutigliani EM, Bokan B, Torang A, van Hooff SR, Zwijnenburg DA, Wouters VM, van de Vlasakker VCJ, Galanos LJK, Nijman LE, Logiantara A, Veenstra VL, Schlingemann S, van Piggelen S, van der Wel N, Krawczyk PM, Platteeuw JJ, Tuynman JB, de Hingh IH, Klomp JPG, Oubrie A, Snaebjornsson P, Medema JP, Oei AL, Kranenburg O, Elbers CC, Lenos KJ, Vermeulen L, Bijlsma MF. Bootsma S, et al. Among authors: van hooff sr. Cell Rep Med. 2024 May 21;5(5):101523. doi: 10.1016/j.xcrm.2024.101523. Epub 2024 Apr 25. Cell Rep Med. 2024. PMID: 38670098 Free PMC article.
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine.
Langenberg KPS, van Hooff SR, Koopmans B, Strijker JGM, Kholosy WM, Ober K, Zwijnenburg DA, van der Hoek JJF, Keller KM, Vernooij L, Schild LG, Looze EJ, Ebus ME, Essing AHW, Vree P, Tas ML, Matser YAH, Wienke J, Volckmann R, Tops BBJ, Kester LA, Badloe S, Hehir-Kwa JY, Kemmeren P, Goemans BF, Zwaan CM, Oehme I, Jäger N, Witt O, van Eijkelenburg NKA, Dierselhuis MP, Tytgat GAM, Wijnen MHW, van Noesel MM, de Krijger RR, Eising S, Koster J, Dolman EM, Molenaar JJ. Langenberg KPS, et al. Among authors: van hooff sr. Eur J Cancer. 2025 Mar 11;218:115275. doi: 10.1016/j.ejca.2025.115275. Epub 2025 Feb 8. Eur J Cancer. 2025. PMID: 39954414 Free PMC article.
Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes.
Cobos FA, Panah MJN, Epps J, Long X, Man TK, Chiu HS, Chomsky E, Kiner E, Krueger MJ, di Bernardo D, Voloch L, Molenaar J, van Hooff SR, Westermann F, Jansky S, Redell ML, Mestdagh P, Sumazin P. Cobos FA, et al. Among authors: van hooff sr. Genome Biol. 2023 Aug 1;24(1):177. doi: 10.1186/s13059-023-03016-6. Genome Biol. 2023. PMID: 37528411 Free PMC article.
Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies.
Keller KM, Krausert S, Gopisetty A, Luedtke D, Koster J, Schubert NA, Rodríguez A, van Hooff SR, Stichel D, Dolman MEM, Vassal G, Pfister SM, Caron HN, Stancato LF, Molenaar JJ, Jäger N, Kool M. Keller KM, et al. Among authors: van hooff sr. Eur J Cancer. 2022 Feb;162:107-117. doi: 10.1016/j.ejca.2021.11.030. Epub 2021 Dec 25. Eur J Cancer. 2022. PMID: 34963094 Free article. Review.
Corrigendum to "Implementation of paediatric precision oncology into clinical practice: The individualized therapies for children with cancer program 'iTHER'" [Eur J Cancer 175 (2022) 311-325].
Langenberg KPS, Meister MT, Bakhuizen JJ, Boer JM, van Eijkelenburg NKA, Hulleman E, Ilan U, Looze EJ, Dierselhuis MP, Lugt JV, Breunis W, Schild LG, Ober K, van Hooff SR, Scheijde-Vermeulen MA, Hiemcke-Jiwa LS, Flucke UE, Kranendonk MEG, Wesseling P, Sonneveld E, Punt S, Boltjes A, van Dijk F, Verwiel ETP, Volckmann R, Hehir-Kwa JY, Kester LA, Koudijs MMJ, Waanders E, Holstege FCP, Vormoor HJ, Hoving EW, Noesel MMV, Pieters R, Kool M, Stumpf M, Blattner-Johnson M, Balasubramanian GP, Van Tilburg CM, Jones BC, Jones DTW, Witt O, Pfister SM, Jongmans MCJ, Kuiper RP, de Krijger RR, Wijnen MHW, den Boer ML, Zwaan CM, Kemmeren P, Koster J, Tops BBJ, Goemans BF, Molenaar JJ. Langenberg KPS, et al. Among authors: van hooff sr. Eur J Cancer. 2025 May 15;221:115423. doi: 10.1016/j.ejca.2025.115423. Epub 2025 Apr 12. Eur J Cancer. 2025. PMID: 40222202 Free PMC article. No abstract available.
Two opposing gene expression patterns within ATRX aberrant neuroblastoma.
van Gerven MR, Schild L, van Arkel J, Koopmans B, Broeils LA, Meijs LAM, van Oosterhout R, van Noesel MM, Koster J, van Hooff SR, Molenaar JJ, van den Boogaard ML. van Gerven MR, et al. Among authors: van hooff sr. PLoS One. 2023 Aug 4;18(8):e0289084. doi: 10.1371/journal.pone.0289084. eCollection 2023. PLoS One. 2023. PMID: 37540673 Free PMC article.
The potential of PARP as a therapeutic target across pediatric solid malignancies.
Keller KM, Koetsier J, Schild L, Amo-Addae V, Eising S, van den Handel K, Ober K, Koopmans B, Essing A, van den Boogaard ML, Langenberg KPS, Jäger N, Kool M, Pfister S, Dolman MEM, Molenaar JJ, van Hooff SR. Keller KM, et al. Among authors: van hooff sr. BMC Cancer. 2023 Apr 5;23(1):310. doi: 10.1186/s12885-022-10319-7. BMC Cancer. 2023. PMID: 37020198 Free PMC article.
42 results